Active Recombinant Human NGF, MIgG2a Fc-tagged
Cat.No. : | NGF-002H |
Product Overview : | The extracellular domain of human NGF(AAI26149.1)(Met1-Ala241) is fused to the N-terminus of the Fc region of mouse IgG2a was expressed in CHO cell. |
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Description : | This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and isincorporated into a larger complex. This protein has nerve growth stimulating activity and the complex isinvolved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons.Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), anddysregulation of this gene"s expression is associated with allergic rhinitis. |
Source : | CHO cell |
Species : | Human |
Tag : | MIgG2a Fc-tagged |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity : | Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. |
Molecular Mass : | 40KDa (monomer) |
AA Sequence : | Met1-Ala241 |
Endotoxin : | <0.06 eu/μg as determined by lal test.>0.06> |
Purity : | >98%, by SDS-PAGE under reducing conditions. |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
Gene Name : | NGF nerve growth factor (beta polypeptide) [ Homo sapiens ] |
Official Symbol : | NGF |
Synonyms : | NGF; nerve growth factor (beta polypeptide); NGFB; beta-nerve growth factor; nerve growth factor, beta subunit; HSAN5; Beta-NGF; MGC161426; MGC161428; |
Gene ID : | 4803 |
mRNA Refseq : | NM_002506 |
Protein Refseq : | NP_002497 |
MIM : | 162030 |
UniProt ID : | P01138 |
Chromosome Location : | 1p13.1 |
Pathway : | ARMS-mediated activation, organism-specific biosystem; Activation of TRKA receptors, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Axonal growth stimulation, organism-specific biosystem; Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; Ceramide signalling, organism-specific biosystem; |
Function : | growth factor activity; nerve growth factor receptor binding; receptor signaling protein activity; |
Products Types
◆ Recombinant Protein | ||
Ngf-258M | Recombinant Active Mouse NGF Protein, His-tagged(C-ter) | +Inquiry |
NGF-814H | Recombinant Human NGF Protein, MYC/DDK-tagged | +Inquiry |
Ngf-1158G | Recombinant Guinea pig Ngf Protein, His-tagged | +Inquiry |
Ngf-489R | Recombinant Rat Ngf Protein(124-241aa), His-tagged | +Inquiry |
Ngf-10602M | Recombinant Mouse Ngf Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
Ngf-51M | Native Mouse Nerve Growth Factor 2.5S | +Inquiry |
Ngf-298M | Active Native Mouse Nerve Growth Factor | +Inquiry |
Ngf-182M | Active Native Mouse Ngf Protein | +Inquiry |
◆ Lysates | ||
NGF-001HCL | Recombinant Human NGF cell lysate | +Inquiry |
NGF-001MCL | Recombinant Mouse NGF cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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