Recombinant Human TIMP1, His-tagged
Cat.No. : | TIMP1-77H |
Product Overview : | Recombinant human TIPM1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | TIMP1, also known as TIMP metalloproteinase inhibitor 1, is a glycoprotein that is expressed from the several tissues of organisms. This protein is a member of the TIMP family. The glycoprotein is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. |
Source : | Insect cell |
Species : | Human |
Tag : | His |
Form : | Liquid. In phosphate buffered saline (pH7.4). |
Molecular Mass : | 21.5kDa (190aa) 18-28KDa (SDS-PAGE under reducing conditions.) |
AA Sequence : | CTCVPPHPQT AFCNSDLVIR AKFVGTPEVN QTTLYQRYEI KMTKMYKGFQ ALGDAADIRF VYTPAMESVC GYFHRSHNRS EEFLIAGKLQ DGLLHITTCS FVAPWNSLSL AQRRGFTKTY TVGCEECTVF PCLSIPCKLQ SGTHCLWTDQ LLQGSEKGFQ SRHLACLPRE PGLCTWQSLR SQIAHHHHHH |
Endotoxin : | < 1.0 eu per 1 microgram of protein (determined by lal |
Purity : | >90% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.2mg/ml (determined by Bradford) |
Gene Name : | TIMP1 TIMP metallopeptidase inhibitor 1 [ Homo sapiens ] |
Official Symbol : | TIMP1 |
Synonyms : | TIMP1; TIMP metallopeptidase inhibitor 1; CLGI, TIMP, tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor); metalloproteinase inhibitor 1; EPO; TIMP-1; collagenase inhibitor; erythroid potentiating activity; erythroid-potentiating activity; fibroblast collagenase inhibitor; tissue inhibitor of metalloproteinases 1; EPA; HCI; CLGI; TIMP; FLJ90373; |
Gene ID : | 7076 |
mRNA Refseq : | NM_003254 |
Protein Refseq : | NP_003245 |
MIM : | 305370 |
UniProt ID : | P01033 |
Chromosome Location : | Xp11.3-p11.23 |
Pathway : | Activation of Matrix Metalloproteinases, organism-specific biosystem; Degradation of the extracellular matrix, organism-specific biosystem; Extracellular matrix organization, organism-specific biosystem; Hemostasis, organism-specific biosystem; IL6-mediated signaling events, organism-specific biosystem; Matrix Metalloproteinases, organism-specific biosystem; Platelet activation, signaling and aggregation, organism-specific biosystem; |
Function : | enzyme inhibitor activity; metal ion binding; metalloendopeptidase inhibitor activity; metalloendopeptidase inhibitor activity; protein binding; |
Products Types
◆ Recombinant Protein | ||
Timp1-410R | Recombinant Rat Timp1 Protein, His-tagged | +Inquiry |
TIMP1-1034M | Recombinant Mouse TIMP1 Protein, His-tagged | +Inquiry |
TIMP1-0058H | Recombinant Human TIMP1 Protein | +Inquiry |
TIMP1-409H | Recombinant Human TIMP1 Protein, His-tagged | +Inquiry |
Timp1-6436M | Active Recombinant Mouse Timp1 Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
TIMP1-30840TH | Native Human TIMP1 | +Inquiry |
TIMP1-91B | Active Native Bovine Thrombin | +Inquiry |
TIMP1-92H | Native Human TIMP-1 | +Inquiry |
◆ Lysates | ||
TIMP1-1490RCL | Recombinant Rat TIMP1 cell lysate | +Inquiry |
TIMP1-2678HCL | Recombinant Human TIMP1 cell lysate | +Inquiry |
TIMP1-2376MCL | Recombinant Mouse TIMP1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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