Recombinant Human Anaplastic Lymphoma Receptor Tyrosine Kinase

• Cat.No.: ALK-65H
• Product Overview: Recombinant human anaplastic lymphoma receptor tyrosine kinase encoding 426-528 a.a. expressed inE.coli,37kDa.

Specification

• Cat. No.: ALK-65H
• Description: ALK/p80 is a human p80 protein, identified as a hybrid of the anaplastic lymphoma kinase (ALK) gene and the nucleophosmin (NPM) gene resulting from the t(2;5)(p23;q35) translocation found in a third of large cell lymphomas.
• Source: Recombinant human ALK/P80 encoding 426-528 a.a. expressed inE.coli.
• Presentation: 100µl purified human ALK/P80 protein at 0.1mg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
• Application And Suggested Dilutions: •ELISA •Inhibition Assays •Western Blotting.
• Characterization: On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 37kDa.
• Activity: Not known.
• Storage: Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12 months.

Gene Information

• Gene Name: ALK anaplastic lymphoma receptor tyrosine kinase [ Homo sapiens ]
• Synonyms: ALK; anaplastic lymphoma receptor tyrosine kinase; CD246; NBLST3; TFG/ALK; ALK tyrosine kinase receptor; EC 2.7.10.1; anaplastic lymphoma kinase (Ki-1); Anaplastic lymphoma kinase
• Gene ID: 238
• mRNA Refseq: NM_001718
• Protein Refseq: NP_001709
• MIM: 105590
• UniProt ID: Q9UM73
• Chromosome Location: 2p23
• Function: ATP binding; nucleotide binding; protein binding; receptor activity; receptor signaling protein tyrosine kinase activity; transferase activity; transmembrane receptor protein tyrosine kinase activity