Recombinant Human CD22 Molecule, Extracellular Domain
| Cat.No. : | CD22-960H |
| Product Overview : | Recombinant Human solube CD22 molecule produced inCHOwas a 75.0kDa (666 amino acid residues) protein which corresponds to the extracellular domain of CD22. |
- Specification
- Gene Information
- Related Products
| Cat. No. : | CD22-960H |
| Description : | CD22 is a 135kDa B-cell restricted sialoglycoprotein that binds to oligosaccharides containing 2-6-linked sialic acid residues. It is present in the cytoplasm of nearly all B-lineage cells and is also expressed on the surface of B-cells during advance stages of differentiation. Although the exact physiological function of CD22 is unclear, it appears to play a role in B-cell activation and to act as an adhesion molecule. The potential therapeutic use of CD22 and anti-CD22 may be useful in diagnostic and/or treatment of leukemia, lymphoma, non-Hodgkin"s lymphoma and certain autoimmune conditions. |
| Source : | CHO cells. |
| Purity : | >95%by SDS-PAGE and HPLC analyses. |
| Endotoxin level : | <0.1ng/ μg of sCD22. |
| Stabilizer : | None. |
| Formulation : | Lyophilized. |
| Biological Activity : | Data not available at this time. |
| Reconstitution : | We recommended a quick spin followed by reconstitution in water to a concentration of 0.1-1.0 mg/ml. This solution can be diluted into other aqueous buffers and stored at 4°C for one week or at –20°C for future use. |
| Stability : | The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C. Reconstituted sCD22 should be stored in working aliquots at -20°C. Avoid repeated freeze-thaw cycles. |
| Gene Name : | CD22 CD22 molecule [ Homo sapiens ] |
| Synonyms : | CD22 CD22 molecule; SIGLEC2; FLJ22814; SIGLEC-2; MGC130020; CD22 antigen; Siglec-2; B-cell receptor CD22; Sialic acid-binding Ig-like lectin 2; Siglec-2; Leu-14; B-lymphocyte cell adhesion molecule; BL-CAM |
| Gene ID : | 933 |
| mRNA Refseq : | NM_001771 |
| Protein Refseq : | NP_001762 |
| MIM : | 107266 |
| UniProt ID : | P20273 |
| Chromosome Location : | 19q13.1 |
| Pathway : | B cell receptor signaling pathway; Cell adhesion molecules (CAMs); Hematopoietic cell lineage |
| Function : | protein binding; sugar binding |
Products Types
| ◆ Lysates | ||
| CD22-1956HCL | Recombinant Human CD22 cell lysate | +Inquiry |
| CD22-001MCL | Recombinant Mouse CD22 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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