"APOA1" Related Products

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Native Human APOA1, Protein A-tagged

Cat.No.: APOA1-26121TH
Product Overview: Full length Human Apolipoprotein A I purified from Human Plasma; amino acids 25-267, MWt 28kDa.
Description: This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis.
Tissue specificity: Major protein of plasma HDL, also found in chylomicrons. Synthesized in the liver and small intestine.
Form: Liquid
Purity: >95% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 10mM Ammonium bicarbonate, pH 7.4
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities: Belongs to the apolipoprotein A1/A4/E family.
Gene Name: APOA1 apolipoprotein A-I [ Homo sapiens ]
Official Symbol: APOA1
Synonyms: APOA1; apolipoprotein A-I;
Gene ID: 335
mRNA Refseq: NM_000039
Protein Refseq: NP_000030
MIM: 107680
Uniprot ID: P02647
Chromosome Location: 11q23-q24
Pathway: ABC-family proteins mediated transport, organism-specific biosystem; ABCA transporters in lipid homeostasis, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Amyloids, organism-specific biosystem;
Function: apolipoprotein A-I receptor binding; apolipoprotein receptor binding; beta-amyloid binding; cholesterol binding; contributes_to cholesterol transporter activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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