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Native Human CTSH

Cat.No.: CTSH-27404TH
Product Overview: Full length native Human Cathepsin H prepared from Human liver; MWt 28 kDa.
Description: The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors.
Biological activity: Activity: greater than 1 unit per mg protein. One unit is defined as the amount of enzyme that hydrolyzes one µmole of L-arginine-beta-napthylamide per minute at 40°C using 75 mM potasium phosphate, pH 6.8, with 1 mM EDTA and 3 mM cysteine as the ac
Form: Liquid
Storage buffer: Preservative: NoneConstituents: 20mM Sodium acetate, 100mM Sodium chloride, 1mM EDTA, pH 4.5
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Gene Name: CTSH cathepsin H [ Homo sapiens ]
Official Symbol: CTSH
Synonyms: CTSH; cathepsin H; CPSB; pro-cathepsin H; ACC 4; ACC 5;
Gene ID: 1512
mRNA Refseq: NM_004390
Protein Refseq: NP_004381
MIM: 116820
Uniprot ID: P09668
Chromosome Location: 15q25.1
Pathway: Lysosome, organism-specific biosystem; Lysosome, conserved biosystem;
Function: cysteine-type endopeptidase activity; cysteine-type peptidase activity; kininogen binding; peptidase activity; protein binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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