Recombinant Human CXCR3, GST-tagged
Cat.No. : | CXCR3-28064TH |
Product Overview : | Recombinant Human CXCR3(121 a.a. - 220 a.a.), fused with GST-tag at N-terminal, was expressed in wheat germ. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4. |
Source : | Wheat germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 36.74 kDa |
AA Sequence : | SGLCKVAGALFNINFYAGALLLACI SFDRYLNIVHATQLYRRGPPARVTL TCLAVWGLCLLFALPDFIFLSAHHD ERLNATHCQYNFPQVGRTALRVLQL |
Applications : | ELISA; WB-Re; AP; Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CXCR3 chemokine (C-X-C motif) receptor 3 [ Homo sapiens (human) ] |
Official Symbol : | CXCR3 |
Synonyms : | CXCR3; chemokine (C-X-C motif) receptor 3; G protein coupled receptor 9 , GPR9; C-X-C chemokine receptor type 3; CD183; CKR L2; CMKAR3; IP10 R; MigR |
Gene ID : | 2833 |
mRNA Refseq : | NM_001142797 |
Protein Refseq : | NP_001136269 |
MIM : | 300574 |
UniProt ID : | P49682 |
Chromosome Location : | Xq13 |
Pathway : | Chemokine receptors bind chemokines; Chemokine signaling pathway; Cytokine-cytokine receptor interaction |
Function : | C-X-C chemokine binding; C-X-C chemokine receptor activity; chemokine receptor activity |
Products Types
◆ Recombinant Protein | ||
CXCR3-1353R | Recombinant Rat CXCR3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Cxcr3-888R | Recombinant Rat Cxcr3 Protein, His-tagged | +Inquiry |
CXCR3-939R | Recombinant Rhesus Macaque CXCR3 Protein, His (Fc)-Avi-tagged | +Inquiry |
CXCR3-261H | Recombinant Human CXCR3 protein, His-tagged | +Inquiry |
CXCR3-16H | Recombinant Human CXCR3 protein, GST-tagged | +Inquiry |
◆ Lysates | ||
CXCR3-7162HCL | Recombinant Human CXCR3 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1196 | cAMP CXCR3 CHO-K1 GPCR Assay Kit | +Inquiry |
Kit-1194 | CXCR3 Activated GPCR Internalization Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket