Recombinant Human MAPKAP1, His-tagged

• Cat.No.: MAPKAP1-29583TH
• Product Overview: Recombinant full length protein, corresponding to amino acids 1-330 of Human SIN1 with N terminal His tag, 55kDa.

Specification

• Description: This gene encodes a protein that is highly similar to the yeast SIN1 protein, a stress-activated protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been described. Alternate polyadenylation sites as well as alternate 3 UTRs have been identified for transcripts of this gene.
• Conjugation: HIS
• Source: E. coli
• Tissue specificity: Ubiquitously expressed, with highest levels in heart and skeletal muscle.
• Form: Lyophilised:Reconstitute with 78 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MTVVTMASARVQDLIGLICWQYTSE GREPKLNDNVSAYCL HIAEDDGEVDTDFPPLDSNEPIHKF GFSTLALVEKYSS PGLTSKESLFVRINAAHGFSLIQVD NTKVTMKEILLKAVKRRKGSQKVSG PQYRLEKQSEPNVAVDLDSTLESQS AWE FCLVRENSSRADGVFEEDSQIDIAT VQDMLSSHHYKSF KVSMIHRLRFTTDVQLGISGDKVEI DPVTNQKASTKFWIK QKPISIDSDLLCACDLAEEKSPSHA IFKLTYLSNHDYK HLYFESDAATVNEIVLKVNYILESR ASTARADYFAQKQ RKLNRRTSFSFQKEKKSGQQ
• Sequence Similarities: Belongs to the SIN1 family.

Gene Information

• Gene Name: MAPKAP1 mitogen-activated protein kinase associated protein 1 [ Homo sapiens ]
• Official Symbol: MAPKAP1
• Synonyms: MAPKAP1; mitogen-activated protein kinase associated protein 1; target of rapamycin complex 2 subunit MAPKAP1; MGC2745; MIP1; SIN1; stress activated protein kinase interacting 1
• Gene ID: 79109
• mRNA Refseq: NM_001006617
• Protein Refseq: NP_001006618
• MIM: 610558
• Uniprot ID: Q9BPZ7
• Chromosome Location: 9q34.11
• Pathway: Adaptive Immune System, organism-specific biosystem; CD28 co-stimulation, organism-specific biosystem; CD28 dependent PI3K/Akt signaling, organism-specific biosystem; CXCR3-mediated signaling events, organism-specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem
• Function: Ras GTPase binding