Recombinant Feline IL2 was expressed in Yeast, therefore does not have endotoxin, is naturally folded, and post-translationally modified.
Interleukin-2 (IL-2) is a cytokine produced by T-helper cells in response to antigenic or mitogenic stimulation. It is required for T-cell proliferation and other activities crucial to the regulation of the immune response. IL-2 was discovered to be a member of a family of cytokines, which also includes IL-4, IL-7, IL-9, IL-15 and IL-21. IL-2 signals through a receptor complex consisting of IL-2 specific IL-2 receptor alpha (CD25), IL-2 receptor beta (CD122) and a common gamma chain (γc). All members of this family use the common gamma chain as part of their signaling complex.
The Feline IL-2 recombinant protein has a predicted molecular weight of 15.4 kDa
APASSSTKET QQQLEQLLLD LRLLLNGVNN PENPKLSRML TFKFYVPKKA TELTHLQCLV EELKPLEEVL YLAQSKNFHL NHIKELMSNI NVTVLKLKGS ETRFTCNYDD ETATIVEFLN KWITFCQSIF STLT
The Feline IL-2 endotoxin-free recombinant protein can be used in cell culture, as an IL-2 ELISA Standard, and as a Western Blot Control.