Recombinant Chicken Interleukin 4

• Cat.No.: IL4-250C
• Product Overview: Recombinant Chicken IL-4 was expressed inYeast.MW= 12.4 kDa (111 aa).

Specification

• Cat. No.: IL4-250C
• Description: Interleukin 4 is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. It was initially identified as a B cell differentiation factor (BCDF), as well as a B cell stimulatory factor (BSF1). Subsequent to the molecular cloning and expression of both human and mouse IL-4, numerous other functions have been described on B cells as well as other hematopoietic and nonhematopoietic cells, including T lymphocytes, monocytes, macrophages, mast cells, myeloid and erythroid progenitors, fibroblasts, endothelial cells, etc. IL-4 exhibits anti-tumor effects both in vivo and in vitro.
• Source: Yeast.
• Formulation/ Reconstitution: Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
• Purification: Ion-exchange chromatography.
• Purity: >85% as visualized by SDS-PAGE analysis.
• Amino Acid Sequence: LQLSVPLMES IRIVNDIQGE VSCVKMNVTD IFADNKTNNK TELLCKASTI VWESQHCHKN LQGLFLNMRQ LLNASSTSLK APCPTAAGNT TSMEKFLADL RTFFHQLAKN K.
• Bioactivity: In testing.
• Stability And Storage: Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.

Gene Information

• Gene Name: IL4 interleukin 4 [ Gallus gallus ]
• Synonyms: interleukin 4; IL4
• Gene ID: 416330
• mRNA Refseq: NM_001007079.1
• Protein Refseq: NP_001007080.1
• Chromosome Location: 13
• Pathway: Cytokine-cytokine receptor interaction; Intestinal immune network for IgA production; Jak-STAT signaling pathway
• Function: growth factor activity; interleukin-4 receptor binding

Reviews

10/17/2021

By testing immunogenicity in animal models, detect whether an immune response is induced.

11/09/2020

The structure of the recombinant protein was analyzed by nuclear magnetic resonance (NMR), X-ray crystallography or electron microscopy, and the results showed that the protein was stable.

05/06/2020

This protein has good stability, and the test results of heat resistance, acid and alkali resistance and protease degradation resistance are good.