Catalog # or name ...
ACE-2 (amino acid Met1~Ser740) encoding the original signal peptide
sequence and the extracellular domain was tagged with FLAG (DYKDDDDK)
at the C-terminus. The tagged protein was expressed in HEK-293
purified from c.
converting enzyme 2 (ACE2) is an exopeptidase that catalyses the
conversion of angiotensin I to the nonapeptide angiotensin,or the
conversion of angiotensin II to angiotensin 1-7. ACE 2 has direct
effects on cardiac functiona, and is expressed predominantly in
vascular endothelial cells of the heart and the kidneys.
>90%, as determined
0.2 m filtered
solution in phosphate-buffered saline.
Hydrolysis of a
fluorescent peptide substrate, Mca-Y-V-A-D-A-P-K(Dnp)-OH.
determined by the LAL method.
proteins should be stored in working aliquots at -20oC for three
months without detectable loss of activity. Avoid repeated
ACE2 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 [
Homo sapiens ]
ACE2; angiotensin I
converting enzyme (peptidyl-dipeptidase A) 2; ACEH; DKFZp434A014;
angiotensin I converting enzyme; ACE-related carboxypeptidase2;
angiotensin converting enzyme-like protein; EC 220.127.116.11; EC
3.4.17.-; Angiotensin-converting enzyme 2; ACEH
activity; chloride ion binding; glycoprotein binding; metal ion
binding; metallopeptidase activity; peptidase activity;
peptidyl-dipeptidase activity; viral receptor activity; zinc ion
PDB rendering based on 1r42.
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