Recombinant Rat Epidermal Growth Factor
Cat.No. : | Egf-460R |
Product Overview : | Recombinant Rat Epidermal Growth Factor is expressed inE. coli. |
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Cat. No. : | Egf-460R |
Description : | EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-α and VGF (vaccinia virus growth factor). Recombinant rat EGF is a 6.2 kDa globular protein containing 54 amino acid residues including 3 intramolecular disulfide-bonds. |
Source : | E. coli. |
Specific Activity : | ≥ 1 x 107units/mg. |
Endotoxin Level : | < 0.1 ng per µg of rRa EGF (1EU/µg). |
Purity : | Greater than 98% (determined by SDS-PAGE and HPLC analysis). |
Biological Activity : | The ED50was determined by a cell proliferation assay using BALB/c 3T3 cells is < 0.1 ng/ml, corresponding to a specific activity of > 1 x 107units/mg. |
Formulation : | Lyophilized from a sterile-filtered solution with no additives. |
Reconstitution : | Please Note: Always centrifuge product before opening vial. The lyophilized protein should be reconstituted with distilled, sterile water to a concentration of 0.1-1.0 mg/ml. For further dilution, carrier protein (0.1% BSA or HSA) should be added to avoid loss of bioactivity. |
Storage & Stability : | The lyophilized protein, though stable at room temperature for up to 3 weeks, is best stored desiccated at -20°C. Reconstituted protein should be used immediately or stored long-term in undiluted working aliquots at -20°C. For long-term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze-thaw cycles. |
Gene Name : | Egf epidermal growth factor [ Rattus norvegicus ] |
Synonyms : | Egf; epidermal growth factor (beta-urogastrone); URG; HOMG4; Pro-epidermal growth factor; Epidermal growth factor; Urogastrone |
Gene ID : | 25313 |
mRNA Refseq : | NM_012842 |
Protein Refseq : | NP_036974 |
UniProt ID : | P07522 |
Chromosome Location : | 2q42-q43 |
Pathway : | Bladder cancer; Cytokine-cytokine receptor interaction; Endocytosis; Endometrial cancer; ErbB signaling pathway; Focal adhesion; Gap junction; Glioma; MAPK signaling pathway; Melanoma; Non-small cell lung cancer; Melanoma; Non-small cell lung cancer; Pancreatic cancer; Pathways in cancer; Prostate cancer; Regulation of actin cytoskeleton |
Function : | calcium ion binding; epidermal growth factor receptor binding; growth factor activity; protein binding |
Products Types
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EGF-2509H | Recombinant Human EGF protein(981-1020 aa), N-MBP & C-His-tagged | +Inquiry |
EGF-333H | Active Recombinant Human EGF Protein (Asn 971 - Arg 1023) | +Inquiry |
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◆ Native Protein | ||
Egf-634M | Active Native Mouse Egf | +Inquiry |
Egf -634M | Active Native Mouse Egf protein | +Inquiry |
EGF-23H | Active Native Human EGF protein | +Inquiry |
◆ Lysates | ||
EGF-973MCL | Recombinant Mouse EGF cell lysate | +Inquiry |
EGF-2716HCL | Recombinant Human EGF cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionThe body naturally produces EGF protein, and it can also be synthesized for clinical applications using biotechnological methods.
Generally, EGF is well-tolerated, but localized irritation or redness at the application site can occur in some cases.
Yes, EGF has been explored for its potential in treating burns by promoting the regeneration of damaged skin tissue.
EGF protein is widely used in clinical settings for wound healing, tissue regeneration, and certain dermatological conditions.
Yes, EGF is a common ingredient in some cosmetic products due to its ability to promote skin rejuvenation and reduce the appearance of fine lines and wrinkles.
Customer Reviews (3)
Write a reviewThis can be advantageous in understanding disease mechanisms and developing novel therapeutics.
The manufacturer can provide detailed documentation on the quality control measures undertaken during protein production and purification.
The manufacturer can offer technical expertise and guidance to researchers regarding the proper use, handling, and storage of EGF protein.
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