Recombinant Bee Phospholipase A2
Cat.No. : | Pla2-343B |
Product Overview : | Recombinant protein produced inE.Colicontains phospholipase P00630 bee venom protein epitopes, 26-162 amino acids. Purified by proprietary chromatographic technique. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Pla2-343B |
Description : | Bee venom phospholipase A2 (PLA) is the main allergen in the bee sting allergy. Bee venom phospholipase A2 (BV-PLA2) is a hydrolytic enzyme which specifically cleaves the sn-2 acyl bond of phospholipids at the lipid/water interface. BV-PLA2 is a 14–16-kDa glycoprotein, consisting of 134 amino acids and displaying a single carbohydrate side chain at the residue Asn13. It is also held to be responsible for some systemic anaphylactic reactions in bee venom sensitized individuals. BV-PLA2 presents 3 peptide and a glycopeptide T cell epitopes, which are recognized by both allergic and non-allergic bee venom sensitized subjects. PLA is able to elicit both IgE mediated allergy and normal immunity to bee sting which usually is associated with high affinity IgG4 anti-PLA antibodies. |
Source : | E.Coli. |
Form : | 10mM Tris-HCl, pH 6.5, 0.1M Sodium Phosphate and 8M urea. |
Purity : | Protein is >95% pure as determined by 10% PAGE (coomassie staining) and RP-HPLC. |
Applications : | Use as an antigen in ELISA and Western Blots. |
Stability : | Five years frozen. One month in solution at room temperature. |
Storage : | Protein is shipped at ambient temperature. Upon arrival, Store at -20°C. |
Gene Name : | Pla2 phospholipase A2 [ Apis mellifera ] |
Synonyms : | Pla2; phospholipase A2; GB13351; allergen Api m 1; phosphatidylcholine 2-acylhydrolase; EC 3.1.1.4 |
Gene ID : | 406141 |
mRNA Refseq : | NM_001011614 |
Protein Refseq : | NP_001011614 |
UniProt ID : | P00630 |
Chromosome Location : | LG13 |
Products Types
◆ Recombinant Protein | ||
PLA2-006B | Recombinant Bee PLA2 Protein | +Inquiry |
◆ Native Protein | ||
Pla2-85A | Active Native Apis mellifera Phospholipase A2 | +Inquiry |
◆ Assay kits | ||
Kit-0698 | Phospholipases A2 (calcium-dependent cytosolic) Assay Kit | +Inquiry |
Kit-0699 | sPLA2 Activity Assay Kit | +Inquiry |
Kit-0696 | cPLA2 Assay Kit | +Inquiry |
Kit-1082 | Phospholipase A2 Activity Assay Kit (Fluorometric) | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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