Recombinant Full Length Human ACAD9 Protein, GST-tagged

• Cat.No.: ACAD9-894HF
• Product Overview: Human ACAD9 full-length ORF ( NP_054768.2, 1 a.a. - 621 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the acyl-CoA dehydrogenase family. Members of this family of proteins localize to the mitochondria and catalyze the rate-limiting step in the beta-oxidation of fatty acyl-CoA. The encoded protein is specifically active toward palmitoyl-CoA and long-chain unsaturated substrates. Mutations in this gene cause acyl-CoA dehydrogenase family member type 9 deficiency. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2010]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 95.2 kDa
• Protein Length: 621 amino acids
• AA Sequence: MSGCGLFLRT TAAARACRGL VVSTANRRLL RTSPPVRAFA KELFLGKIKK KEVFPFPEVS QDELNEINQF LGPVEKFFTE EVDSRKIDQE GKIPDETLEK LKSLGLFGLQ VPEEYGGLGF SNTMYSRLGE IISMDGSITV TLAAHQAIGL KGIILAGTEE QKAKYLPKLA SGEHIAAFCL TEPASGSDAA SIRSRATLSE DKKHYILNGS KVWITNGGLA NIFTVFAKTE VVDSDGSVKD KITAFIVERD FGGVTNGKPE DKLGIRGSNT CEVHFENTKI PVENILGEVG DGFKVAMNIL NSGRFSMGSV VAGLLKRLIE MTAEYACTRK QFNKRLSEFG LIQEKFALMA QKAYVMESMT YLTAGMLDQP GFPDCSIEAA MVKVFSSEAA WQCVSEALQI LGGLGYTRDY PYERILRDTR ILLIFEGTNE ILRMYIALTG LQHAGRILTT RIHELKQAKV STVMDTVGRR LRDSLGRTVD LGLTGNHGVV HPSLADSANK FEENTYCFGR TVETLLLRFG KTIMEEQLVL KRVANILINL YGMTAVLSRA SRSIRIGLRN HDHEVLLANT FCVEAYLQNL FSLSQLDKYA PENLDEQIKK VSQQILEKRA YICAHPLDRT C
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ACAD9 acyl-CoA dehydrogenase family, member 9 [ Homo sapiens ]
• Official Symbol: ACAD9
• Synonyms: ACAD9; acyl-CoA dehydrogenase family, member 9; acyl Coenzyme A dehydrogenase family, member 9; acyl-CoA dehydrogenase family member 9, mitochondrial; MGC14452; NPD002; very-long-chain acyl-CoA dehydrogenase VLCAD; acyl-Coenzyme A dehydrogenase family, member 9; FLJ23533
• Gene ID: 28976
• mRNA Refseq: NM_014049
• Protein Refseq: NP_054768
• MIM: 611103
• UniProt ID: Q9H845

Reviews

12/23/2019

Provides high-quality results in detecting and measuring the activity of oxidoreductases in oxidoreductase assays.

02/15/2018

Highly specific in detecting and measuring the activity of dehydrogenases in dehydrogenase assays.

Q&As

What is the structure of this protein and how does it relate to its function?

The protein structure of acyl-CoA dehydrogenase family member 9 includes a flavin adenine dinucleotide (FAD) binding domain.

What diseases or disorders are associated with mutations in this protein?

Mutations in this protein are associated with various metabolic disorders, including mitochondrial fatty acid oxidation disorders.

What are the physiological roles of acyl-CoA dehydrogenase family member 9?

The physiological roles of acyl-CoA dehydrogenase family member 9 are still being investigated.

What is the primary function of acyl-CoA dehydrogenase family member 9 protein?

The primary function of acyl-CoA dehydrogenase family member 9 protein is currently unknown.

Are there any known inhibitors or activators of this protein?

There are currently no known inhibitors or activators of this protein.

What research is currently being conducted to further understand the function of acyl-CoA dehydrogenase family member 9?

Research is ongoing to further understand the function and role of acyl-CoA dehydrogenase family member 9 in cellular metabolism and disease.

How does the activity of this protein contribute to cellular metabolism?

The activity of this protein contributes to fatty acid metabolism and energy production.

How is the expression of acyl-CoA dehydrogenase family member 9 regulated?

The expression of acyl-CoA dehydrogenase family member 9 is regulated by a variety of factors, including gene expression and protein degradation pathways.

What is the cellular location of this protein within the cell?

The cellular location of this protein within the cell is the mitochondria.

What are the substrates that can be acted upon by acyl-CoA dehydrogenase family member 9?

Acyl-CoA dehydrogenase family member 9 can act on medium to long-chain fatty acids.