Recombinant Full Length Human ADAM22 Protein, GST-tagged

• Cat.No.: ADAM22-883HF
• Product Overview: Human ADAM22 full-length ORF ( AAH36029.1, 1 a.a. - 342 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.[provided by RefSeq, Dec 2010]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 65.9 kDa
• Protein Length: 342 amino acids
• AA Sequence: MQAAVAVSVP FLLLCVLGTC PPARCGQAGD ASLMELEKRK ENRFVERQSI VPLRLIYRSG GEDESRHDAL DTRVRGDVGG PQLTHVDQAS FQVDAFGTSF ILDVVLNHDL LSSEYIERHI EHGGKTVEVK GGEHCYYQGH IRGNPDSFVA LSTCHGLHGM FYDGNHTYLI EPEENDTTQE DFHFHSVYKS RLFEFSLDDL PSEFQQVNIT PSKFILKPRP KRSKRQLRRY PRNVEEETKY IELMIVNDHL MFKKHRLSVV HTNTYAKSVV NMADLIYKDQ LKTRIVLVAM ETWATDNKFA ISENPLITLR EFMKYRRDFI KEKSDAVHLF SYVTSVMMYY FF
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ADAM22 ADAM metallopeptidase domain 22 [ Homo sapiens ]
• Official Symbol: ADAM22
• Synonyms: ADAM22; ADAM metallopeptidase domain 22; a disintegrin and metalloproteinase domain 22; disintegrin and metalloproteinase domain-containing protein 22; MDC2; metalloproteinase like; disintegrin like; and cysteine rich protein 2; metalloproteinase-disintegrin ADAM22-3; metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2; ADAM 22; MGC149832
• Gene ID: 53616
• mRNA Refseq: NM_004194
• Protein Refseq: NP_004185
• MIM: 603709
• UniProt ID: Q9P0K1

Reviews

11/10/2022

The company provides one-stop service, from the purchase of products to the completion of experiments in one go.

03/01/2021

The purity of the proteins supplied by your company was very high and satisfactory results were obtained.

12/20/2020

The company provided detailed information about the ADAM22 protein, which made my experiment go smoothly!

Q&As

Where is ADAM22 mainly expressed?

ADAM22 is widely expressed in the brain.

What is the function of the ADAM22?

ADAM22 is a potential cell adhesion molecule.

What is the relationship between ADAM22 and protein 14-3-3β?

ADAM22 interacts with protein 14-3-3β.

Which proteins have the highest homology to ADAM22?

ADAM11 and ADAM23 have the highest homology to ADAM22.

In which diseases is ADAM22 primarily used in research?

ADAM22 is currently being used in studies of diseases such as breast and stomach cancer.