ADAM19
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Official Full Name
ADAM metallopeptidase domain 19
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Overview
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase, which may be involved in normal physiological processes such as cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. It is proposed to play a role in pathological processes, such as cancer, inflammatory diseases, renal diseases, and Alzheimers disease. [provided by RefSeq, May 2013] -
Synonyms
ADAM19; ADAM metallopeptidase domain 19; MLTNB; FKSG34; MADDAM; disintegrin and metalloproteinase domain-containing protein 19; ADAM 19; meltrin-beta; metalloprotease-disintegrin meltrin beta; metalloprotease and disintegrin dendritic antigen marker; a disintegrin and metalloproteinase domain 19 (meltrin beta);
- Cell & Tissue Lysates
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Mus musculus (Mouse)
- E.coli
- E.coli expression system
- HEK293
- Mammalian Cell
- His
- His (Fc)
- Avi
- N/A
- N
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | ADAM19-9038HCL | Recombinant Human ADAM19 293 Cell Lysate | HEK293 | N/A |
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| Human | ADAM19-0046H | Recombinant Human ADAM19 Protein (Gly326-Ser699), N-His-tagged | E.coli | N-His | Gly326-Ser699 |
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| Mouse | ADAM19-1281M | Recombinant Mouse ADAM19 Protein | Mammalian Cell | His |
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| Mouse | ADAM19-310M-B | Recombinant Mouse ADAM19 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | ADAM19-310M | Recombinant Mouse ADAM19 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mus musculus (Mouse) | RFL-30771MF | Recombinant Full Length Mouse Disintegrin And Metalloproteinase Domain-Containing Protein 19(Adam19) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (205-920) |
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| Chicken | ADAM19-4129C | Recombinant Chicken ADAM19 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- ADAM19 Related Articles
- ADAM19 Related Research Area
ADAM19 involved in several pathways and played different roles in them. We selected most pathways ADAM19 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAM19 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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ADAM19 has several biochemical functions, for example, SH3 domain binding, metalloendopeptidase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAM19 itself. We selected most functions ADAM19 had, and list some proteins which have the same functions with ADAM19. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| SH3 domain binding | MVB12A;NCKIPSD;EPS15;SH3BP5;EVLB;QKIA;DOCK1;SH3BP1;WIPF3 |
| metalloendopeptidase activity | ASTL;UQCRC2A;ADAM8A;ADAMDEC1;ADAM33;ADAM21;YME1L1;MMP14;PITRM1 |
| zinc ion binding | WT1;TRIM71;L3MBTL2;MARCH5;RERE;TRIM48;WBP2NL;ZCCHC2;RTN4IP1 |
ADAM19 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAM19 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAM19.
ABI2; UBC; ESF1
- Q&As
- Reviews
Q&As (14)
Ask a questionProdomain, metalloprotease domain, disintegrin domain, cysteine-rich domain, EGF-like domain, transmembrane domain, and cytoplasmic tail.
ADAM19 is located in the Golgi apparatus.
Yes, you can communicate specific requirements with our experts.
We can remove endotoxins according to your needs.
Yes, we provide bacterial expression systems, baculovirus-insect cell expression systems, cell-free in vitro protein expression systems, mammalian expression systems, yeast expression systems and other expression systems.
ADAM19 has been used in related studies such as tumors, inflammatory diseases, and cardiovascular diseases.
Western blotting of ADAM19 can be performed using PVDF membranes.
ADAM19 is expressed at high levels in bone, heart and lung.
This depends on stock availability, or you can tell us your preference.
Yes, you have direct access to our experts who can provide advice tailored to your specific situation.
ADAM19's spot product is currently this one, but we can provide customized production of other ADAM19.
ADAM19 has constitutive α-secretase activity for amyloid precursor protein.
ADAM19 is more active at basic pH.
You can make this request with our staff at the time of purchase.
Customer Reviews (3)
Write a reviewI have purchased protein products that meet my requirements. Although the customization time will be longer, the experimental results are very good.
I just caught up with the promotional offer and got a satisfying protein at an affordable price.
The product parameters are consistent with the information provided before, and the technicians are always able to answer my questions in a timely manner
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