Recombinant Full Length Human ADD1 Protein, GST-tagged
Cat.No. : | ADD1-907HF |
Product Overview : | Human ADD1 full-length ORF ( AAH42998, 1 a.a. - 662 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described. [provided by RefSeq, Jul 2008] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 98.56 kDa |
Protein Length : | 662 amino acids |
AA Sequence : | MNGDSRAAVV TSPPPTTAPH KERYFDRVDE NNPEYLRERN MAPDLRQDFN MMEQKKRVSM ILQSPAFCEE LESMIQEQFK KGKNPTGLLA LQQIADFMTT NVPNVYPAAP QGGMAALNMS LGMVTPVNDL RGSDSIAYDK GEKLLRCKLA AFYRLADLFG WSQLIYNHIT TRVNSEQEHF LIVPFGLLYS EVTASSLVKI NLQGDIVDRG STNLGVNQAG FTLHSAIYAA RPDVKCVVHI HTPAGAAVSA MKCGLLPISP EALSLGEVAY HDYHGILVDE EEKVLIQKNL GPKSKVLILR NHGLVSVGES VEEAFYYIHN LVVACEIQVR TLASAGGPDN LVLLNPEKYK AKSRSPGSPV GEGTGSPPKW QIGEQEFEAL MRMLDNLGYR TGYPYRYPAL REKSKKYSDV EVPASVTGYS FASDGDSGTC SPLRHSFQKQ QREKTRWLNS GRGDEASEEG QNGSSPKSKT KWTKEDGHRT STSAVPNLFV PLNTNPKEVQ EMRNKIREQN LQDIKTAGPQ SQVLCGVVMD RSLVQDAPLS DCTETIEGLE LTEQTFSPAK SLSFRKGELV TASKAIIEKE YQPHVIVSTT GPNPFTTLTD RELEEYRREV ERKQKGSEEN LDEAREQKEK SPPDQPAVPH PPPSTPIKLE EGDGCAREYL LP |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ADD1 adducin 1 (alpha) [ Homo sapiens ] |
Official Symbol : | ADD1 |
Synonyms : | ADD1; adducin 1 (alpha); alpha-adducin; erythrocyte adducin alpha subunit; ADDA; MGC3339; MGC44427 |
Gene ID : | 118 |
mRNA Refseq : | NM_001119 |
Protein Refseq : | NP_001110 |
MIM : | 102680 |
UniProt ID : | P35611 |
Products Types
◆ Recombinant Protein | ||
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ADD1-339M | Recombinant Mouse ADD1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Add1-492M | Recombinant Mouse Add1 Protein, His-tagged | +Inquiry |
ADD1-178R | Recombinant Rat ADD1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ADD1-9017HCL | Recombinant Human ADD1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionSpecific antibodies or probes can be developed to visualize the localization of ADD1 in live cells or tissues.
Altering the expression level or activity of ADD1 can affect cellular processes like cell proliferation, differentiation, or apoptosis.
The expression of ADD1 can change under different physiological or pathological conditions.
ADD1 exhibits subcellular localization in various cellular compartments, such as the nucleus or cytoplasm.
ADD1 interacts with specific binding proteins or partners in a context-dependent manner.
The tissue-specific expression pattern of ADD1 varies across organs and cell types.
ADD1 undergoes post-translational modifications, including phosphorylation and acetylation, which can impact its activity and stability.
There may exist small molecule inhibitors or activators that can modulate ADD1's function, with distinct mechanisms of action.
Specific domains or motifs within ADD1 are responsible for its functional activities.
ADD1 regulates downstream target genes or signaling pathways that contribute to its biological functions.
Customer Reviews (3)
Write a reviewHighly effective in detecting and quantifying the expression levels of fusion proteins in protein expression analysis.
Highly specific in detecting the target protein in tissue sections in immunohistochemistry experiments.
Demonstrates high selectivity and sensitivity in detecting protein-protein interactions in pull-down assays.
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