Recombinant Full Length Human AGPAT6 Protein, GST-tagged

• Cat.No.: AGPAT6-934HF
• Product Overview: Human AGPAT6 full-length ORF ( NP_848934.1, 1 a.a. - 456 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Lysophosphatidic acid acyltransferases (EC 2.3.1.51) catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA). LPA and PA are involved in signal transduction and lipid biosynthesis.[supplied by OMIM, Apr 2004]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 78.5 kDa
• Protein Length: 456 amino acids
• AA Sequence: MFLLLPFDSL IVNLLGISLT VLFTLLLVFI IVPAIFGVSF GIRKLYMKSL LKIFAWATLR MERGAKEKNH QLYKPYTNGI IAKDPTSLEE EIKEIRRSGS SKALDNTPEF ELSDIFYFCR KGMETIMDDE VTKRFSAEEL ESWNLLSRTN YNFQYISLRL TVLWGLGVLI RYCFLLPLRI ALAFTGISLL VVGTTVVGYL PNGRFKEFMS KHVHLMCYRI CVRALTAIIT YHDRENRPRN GGICVANHTS PIDVIILASD GYYAMVGQVH GGLMGVIQRA MVKACPHVWF ERSEVKDRHL VAKRLTEHVQ DKSKLPILIF PEGTCINNTS VMMFKKGSFE IGATVYPVAI KYDPQFGDAF WNSSKYGMVT YLLRMMTSWA IVCSVWYLPP MTREADEDAV QFANRVKSAI ARQGGLVDLL WDGGLKREKV KDTFKEEQQK LYSKMIVGNH KDRSRS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: AGPAT6 1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta) [ Homo sapiens ]
• Official Symbol: AGPAT6
• Synonyms: AGPAT6; 1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta); glycerol-3-phosphate acyltransferase 6; DKFZp586M1819; LPAAT zeta; 1-AGP acyltransferase 6; lysophosphatidic acid acyltransferase zeta; testis spermatogenesis apoptosis-related protein 7; 1-acyl-sn-glycerol-3-phosphate acyltransferase zeta; LPAATZ; TSARG7; 1-AGPAT 6; LPAAT-zeta
• Gene ID: 137964
• mRNA Refseq: NM_178819
• Protein Refseq: NP_848934
• MIM: 608143
• UniProt ID: Q86UL3

Reviews

04/11/2022

 The product’s ability to modulate signal pathways played a crucial role in our discoveries.

09/03/2019

 Replicating outcomes across different cell types showcased the product’s consistent behavior.

01/02/2019

 Compatibility with a range of assays expanded our experimental possibilities significantly.

09/02/2018

The consistent outcomes obtained with the product validated its role in our experimental models.

08/17/2018

It's innovative features allowed us to explore previously uncharted cellular mechanisms.

Q&As

Can AGPAT6’s involvement affect lipid storage mechanisms

How does AGPAT6 contribute to cellular membrane structure

How is AGPAT6’s specific role studied within lipid metabolism

In which cellular compartments can AGPAT6 be found

How is AGPAT6’s participation linked to lipid homeostasis

How does AGPAT6’s function relate to the properties of lipid bilayers

Is AGPAT6 involved in the diversification of phospholipids

Does AGPAT6 respond to stress by altering its function

How is AGPAT6’s impact on overall cellular health studied

Does AGPAT6 influence lipid droplet dynamics within cells

Can AGPAT6’s role intersect with intracellular signaling

How does AGPAT6 impact lipid-mediated signaling pathways

How is AGPAT6’s role related to the production of lipid second messengers

What is the specific function of AGPAT6 in lipid metabolism

How is AGPAT6’s role explored within disease contexts

Does AGPAT6’s malfunction lead to lipid-related disorders

In what manner does AGPAT6 influence membrane dynamics

Can AGPAT6 influence cellular responses to stress

Does AGPAT6’s role vary based on cell type and function

Can AGPAT6 be targeted for therapeutic interventions

Does AGPAT6 contribute to maintaining organelle integrity

Can AGPAT6’s enzymatic action alter lipid composition

Can AGPAT6’s enzymatic activity be regulated by signals

How does AGPAT6’s role relate to maintaining lipid bilayer stability