Recombinant Full Length Human ALKBH8 Protein, C-Flag-tagged
Cat.No. : | ALKBH8-1952HFL |
Product Overview : | Recombinant Full Length Human ALKBH8 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
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Description : | Enables tRNA (uracil) methyltransferase activity; tRNA binding activity; and zinc ion binding activity. Involved in cellular response to DNA damage stimulus; tRNA methylation; and tRNA wobble uridine modification. Located in cytosol and nuclear body. Implicated in autosomal recessive non-syndromic intellectual disability. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 75 kDa |
AA Sequence : | MDSNHQSNYKLSKTEKKFLRKQIKA KHTLLRHEGIETVSYATQSLVVANG GLGNGVSRNQLLPVLEKCGL VDALLMPPNKPYSFARYRTTEESKR AYVTLNGKEVVDDLGQKITLYLNFV EKVQWKELRPQALPPGLMVV EEIISSEEEKMLLESVDWTEDTDNQ NSQKSLKHRRVKHFGYEFHYENNNV DKDKPLSGGLPDICESFLEK WLRKGYIKHKPDQMTINQYEPGQGI PAHIDTHSAFEDEIVSLSLGSEIVM DFKHPDGIAVPVMLPRRSLL VMTGESRYLWTHGITCRKFDTVQAS ESLKSGIITSDVGDLTLSKRGLRTS FTFRKVRQTPCNCSYPLVCD SQRKETPPSFPESDKEASRLEQEYV HQVYEEIAGHFSSTRHTPWPHIVEF LKALPSGSIVADIGCGNGKY LGINKELYMIGCDRSQNLVDICRER QFQAFVCDALAVPVRSGSCDACISI AVIHHFATAERRVAALQEIV RLLRPGGKALIYVWAMEQEYNKQKS KYLRGNRNSQGKKEEMNSDTSVQRS LVEQMRDMGSRDSASSVPRI NDSQEGGCNSRQVSNSKLPVHVNRT SFYSQDVLVPWHLKGNPDKGKPVEP FGPIGSQDPSPVFHRYYHVF REGELEGACRTVSDVRILQSYYDQG NWCVILQKA TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Gene Name : | ALKBH8 alkB homolog 8, tRNA methyltransferase [ Homo sapiens (human) ] |
Official Symbol : | ALKBH8 |
Synonyms : | ABH8; TRM9; MRT71; TRMT9; TRMT9A |
Gene ID : | 91801 |
mRNA Refseq : | NM_138775.3 |
Protein Refseq : | NP_620130 |
MIM : | 613306 |
UniProt ID : | Q96BT7 |
Products Types
◆ Recombinant Protein | ||
Alkbh8-1603M | Recombinant Mouse Alkbh8 Protein, Myc/DDK-tagged | +Inquiry |
ALKBH8-322H | Recombinant Human ALKBH8 Protein, His (Fc)-Avi-tagged | +Inquiry |
ALKBH8-479M | Recombinant Mouse ALKBH8 Protein, His (Fc)-Avi-tagged | +Inquiry |
ALKBH8-3274B | Recombinant Bovine ALKBH8, His-tagged | +Inquiry |
ALKBH8-479H | Recombinant Human ALKBH8 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
ALKBH8-18HCL | Recombinant Human ALKBH8 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (16)
Ask a questionThe mutation of ALKBH8 gene is related to individual heredity, age, gender and so on.
Mutations in the ALKBH8 gene can be regulated and influenced by a healthy lifestyle.
There is currently no specific treatment for the ALKBH8 gene mutation, but treatments can be tailored to the symptoms that occur.
The ALKBH8 gene has been linked to breast cancer, neurological diseases and more.
Mutations in the ALKBH8 gene may affect the body's immunity, but the exact extent of the impact needs to be further studied.
The ALKBH8 gene may affect the immune system, but the specific mechanism needs to be further studied.
ALKBH8 gene is expressed in various tissues, including breast, ovary, kidney, brain and so on.
Mutations in the ALKBH8 gene may cause some genetic diseases.
Mutations in the ALKBH8 gene may lead to long-term health consequences that need to be studied further.
The expression of ALKBH8 gene may be related to cell apoptosis, DNA repair and other physiological processes.
The mutation of ALKBH8 gene may be inherited, and the specific inheritance mode needs to be further studied.
Mutations in the ALKBH8 gene can be diagnosed by methods such as gene sequencing.
The mutation of ALKBH8 gene may be related to environmental factors such as chemicals and radiation.
Mutation of ALKBH8 gene may cause damage to DNA repair, resulting in cell apoptosis obstruction, cell mutation and other problems.
Mutations in the ALKBH8 gene may affect fertility, but the exact extent needs to be further studied.
There is currently no specific cure for mutations in the ALKBH8 gene.
Customer Reviews (3)
Write a reviewGood stability and activity during long-term storage.
It is effective and safe in clinical treatment.
ALKBH8 is not structurally or functionally defective.
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