Recombinant Full Length Human ALS2CR12 Protein, GST-tagged
Cat.No. : | ALS2CR12-1518HF |
Product Overview : | Human ALS2CR12 full-length ORF (AAH31603.1, 1 a.a. - 422 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | ALS2CR12 (Amyotrophic Lateral Sclerosis 2 Chromosome Region Candidate 12) is a Protein Coding gene. Diseases associated with ALS2CR12 include Amyotrophic Lateral Sclerosis 2, Juvenile and Lateral Sclerosis. |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 72.82 kDa |
Protein Length : | 422 amino acids |
AA Sequence : | MYPNPLIYCT CWDPWNLGPR KLIKTPQLPR KNSTGSSKLT PLLPAPKNHN YLQPTKPVVS PKMKIHSARQ EETNKSFYEV INVSPGYQLV RNREQISVTL GDEMFDRKKR WESEIPDKGR FSRTNIISDL EEQISELTAI IEQMNRDHQS AQKLLSSEMD LRCAEMKQNF ENKNRELKEA HEAELSELEN NYKAALKAEK LAAQEKLEEM GKEYKYLKNM FRTYQDSIYD EMEEKWSKQK AKWKKDEKFE RENILLQQKK KMTKKFEMES GEEDKKINES CSAVFENFIQ EKEELLKQHQ SDTLQLEELR KTKEVMQEEL HAQALILESL NTNLYYTQLE LQKEKAIVGN LEKMLQTKFA ETEEKYKHTI QILTEENIHL KQKIISKNEE ICEGCSGRLA SITVSKDDSD TVQDGSKKGQ ES |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ALS2CR12 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12 [ Homo sapiens ] |
Official Symbol : | ALS2CR12 |
Synonyms : | ALS2CR12; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12; amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein |
Gene ID : | 130540 |
mRNA Refseq : | NM_001127391 |
Protein Refseq : | NP_001120863 |
MIM : | 619796 |
UniProt ID : | Q96Q35 |
Products Types
◆ Recombinant Protein | ||
ALS2CR12-493M | Recombinant Mouse ALS2CR12 Protein, His (Fc)-Avi-tagged | +Inquiry |
ALS2CR12-299R | Recombinant Rat ALS2CR12 Protein, His (Fc)-Avi-tagged | +Inquiry |
ALS2CR12-9601H | Recombinant Human ALS2CR12, His-tagged | +Inquiry |
ALS2CR12-643R | Recombinant Rat ALS2CR12 Protein | +Inquiry |
ALS2CR12-506H | Recombinant Human ALS2CR12 protein, GST-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionTargeting ALS2CR12 or its associated pathways could hold potential therapeutic strategies for neurological disorders, aiming to modulate cell cycle regulation, promote neuronal survival, or enhance synaptic plasticity.
The enzymatic activities of ALS2CR12 are not well-characterized, and further studies are required to determine its potential substrates or targets.
ALS2CR12 may interact with proteins involved in cellular processes such as membrane trafficking, cytoskeleton organization, or cellular signaling cascades.
ALS2CR12 contains conserved domains, such as protein-protein interaction domains or functional motifs, which contribute to its molecular functions and interactions.
ALS2CR12 is involved in neuronal development and may affect processes such as neurite outgrowth, dendritic arborization, or synaptic plasticity through its interactions with other molecules.
ALS2CR12 exhibits a broad tissue expression pattern, with higher expression levels observed in the brain, particularly in specific regions associated with neuronal function.
Post-translational modifications, such as phosphorylation or ubiquitination, may regulate ALS2CR12 activity, localization, or its interactions with other proteins.
ALS2CR12 is implicated in cell cycle regulation, apoptosis, or signaling pathways involved in neuronal development and synaptic function.
Limited evidence links genetic variations or mutations in ALS2CR12 to neurological disorders or pathological conditions, requiring further investigation.
ALS2CR12 localizes to various subcellular compartments, including the cytoplasm, plasma membrane, and potentially the endoplasmic reticulum or mitochondria.
Customer Reviews (3)
Write a reviewEfficient removal of contaminants during protein purification.
User-friendly instrument for protein characterization.
Low assay variability for reproducible results.
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