ALS2CR8
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Official Full Name
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8
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Overview
Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein also known as calcium-response factor (CaRF) is a protein that in humans is encoded by the ALS2CR8 gene. -
Synonyms
ALS2CR8; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8; amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein; calcium response factor; CaRF; FLJ21579; NYD SP24; calcium-response factor; testis development;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Rat
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | ALS2CR8-9603H | Recombinant Human ALS2CR8, GST-tagged | E.coli | GST | 1-311a.a. | |
Human | ALS2CR8-509H | Recombinant Human ALS2CR8 protein, GST-tagged | Wheat Germ | GST | ||
Human | ALS2CR8-68HCL | Recombinant Human ALS2CR8 cell lysate | N/A | |||
Human | ALS2CR8-1303HF | Recombinant Full Length Human ALS2CR8 Protein, GST-tagged | In Vitro Cell Free System | GST | 718 amino acids | |
Rat | ALS2CR8-644R | Recombinant Rat ALS2CR8 Protein | Mammalian Cell | His | ||
Rat | ALS2CR8-300R | Recombinant Rat ALS2CR8 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | ALS2CR8-300R-B | Recombinant Rat ALS2CR8 Protein Pre-coupled Magnetic Beads | HEK293 |
- Involved Pathway
- Protein Function
- Interacting Protein
- ALS2CR8 Related Research Area
ALS2CR8 involved in several pathways and played different roles in them. We selected most pathways ALS2CR8 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ALS2CR8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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ALS2CR8 has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ALS2CR8 itself. We selected most functions ALS2CR8 had, and list some proteins which have the same functions with ALS2CR8. You can find most of the proteins on our site.
Function | Related Protein |
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DNA binding | GABPA;KAT6A;NKX3.3;TERFA;DEDD;PAX2;NFE2L1A;KCNA3;HOXA5 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding | EBF1;TCF4;T;BATF3;PAXBP1;MED8;CEBPE;ZNF460;HELT |
transcription factor activity, sequence-specific DNA binding | PA2G4;NFIL3-4;NR2F2;E2F7;ZNF41;FOXC1A;EGR3;MAFA;MECOM |
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | HLTF;FOXJ1;ATF4;ZNF750;HEYL;ESRRA;ZIC3;OTX2;WT1 |
ALS2CR8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALS2CR8 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALS2CR8.
saicar; PKM; purCD; LMO3
- Q&As
- Reviews
Q&As (10)
Ask a questionThe enzymatic activities of ALS2CR8 are not well-characterized, and further studies are needed to identify its potential substrates or targets.
ALS2CR8 undergoes specific post-translational modifications, including phosphorylation or ubiquitination, that regulate its activity, stability, or subcellular localization.
ALS2CR8 plays a role in synaptic function, affecting processes such as neurotransmitter release, postsynaptic receptor trafficking, or synaptic vesicle dynamics.
Targeting ALS2CR8 or its associated pathways may hold therapeutic potential for treating neurological disorders, aiming to modulate synaptic function, promote neuronal survival, or enhance neuronal connectivity.
ALS2CR8 is implicated in intracellular signaling pathways, such as those involved in neuronal survival, synaptic plasticity, or gene expression regulation.
ALS2CR8 expression is dynamically regulated during neuronal development and can be influenced by factors such as neuronal activity, neurotrophic factors, or signaling molecules.
ALS2CR8 is crucial for neuronal development and function, potentially influencing processes such as neurite outgrowth, synaptogenesis, or synaptic transmission through various molecular mechanisms.
ALS2CR8 interacts with specific proteins or molecular complexes involved in neuronal signaling, cytoskeletal organization, or intracellular transport, which contribute to its cellular functions.
ALS2CR8 is primarily localized to the cytoplasm, with potential associations with specific cellular compartments involved in neuronal function.
ALS2CR8 contains functional domains and motifs, such as protein-protein interaction domains or enzymatic domains, that play a role in its molecular functions.
Customer Reviews (3)
Write a reviewCompatible with automated liquid handling systems.
Accurate assessment of protein expression changes.
Low interference from endogenous proteins in samples.
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