Recombinant Full Length Human ARHGAP28 Protein, GST-tagged
Cat.No. : | ARHGAP28-1323HF |
Product Overview : | Human ARHGAP28 full-length ORF ( AAH65274.1, 1 a.a. - 545 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | ARHGAP28 (Rho GTPase Activating Protein 28) is a Protein Coding gene. Diseases associated with ARHGAP28 include Benign Meningioma and Central Nervous System Organ Benign Neoplasm. Among its related pathways are Signaling by GPCR and p75 NTR receptor-mediated signalling. GO annotations related to this gene include GTPase activator activity. An important paralog of this gene is ARHGAP18. |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 88.4 kDa |
Protein Length : | 545 amino acids |
AA Sequence : | MNELPRDTCG NHTNQLDGTK EERELPRVIK TSGSMPDDAS LNSTTLSDAS QDKEGSFAVP RSDSVAILET IPVLPVHSNG SPEPGQPVQN AISDDDFLEK NIPPEAEELS FEVSYSEMVT EALKRNKLKK SEIKKEDYVL TKFNVQKTRF GLTEAGDLSA EDMKKIRHLS LIELTAFFDA FGIQLKRNKT EKVKGRDNGI FGVPLTVLLD GDRKKDPGVK VPLVLQKFFE KVEESGLESE GIFRLSGCTA KVKQYREELD AKFNADKFKW DKMCHREAAV MLKAFFRELP TSLFPVEYIP AFISLMERGP HVKVQFQALH LMVMALPDAN RDAAQALMTF FNKVIANESK NRMSLWNIST VMAPNLFFSR SKHSDYEELL LANTAAHIIR LMLKYQKILW KVPSFLITQV RRMNEATMLL KKQLPSVRKL LRRKTLERET ASPKTSKVLQ KSPSARRMSD VPEGVIRVHA PLLSKVSMAI QLNNQTKAKD ILAKFQYENR ILHWQRAALS FLNGKWVKKE REESTETNRS PKHVFLFTIG LDIST |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ARHGAP28 Rho GTPase activating protein 28 [ Homo sapiens ] |
Official Symbol : | ARHGAP28 |
Synonyms : | ARHGAP28; Rho GTPase activating protein 28; rho GTPase-activating protein 28; FLJ10312; KIAA1314; rho-type GTPase-activating protein 28; FLJ27160; DKFZp686A2038 |
Gene ID : | 79822 |
mRNA Refseq : | NM_001010000 |
Protein Refseq : | NP_001010000 |
MIM : | 610592 |
UniProt ID : | Q9P2N2 |
Products Types
◆ Recombinant Protein | ||
ARHGAP28-677M | Recombinant Mouse ARHGAP28 Protein, His (Fc)-Avi-tagged | +Inquiry |
ARHGAP28-1867M | Recombinant Mouse ARHGAP28 Protein | +Inquiry |
ARHGAP28-768H | Recombinant Human ARHGAP28 protein, GST-tagged | +Inquiry |
ARHGAP28-2950H | Recombinant Human ARHGAP28 protein, His-tagged | +Inquiry |
ARHGAP28-1813Z | Recombinant Zebrafish ARHGAP28 | +Inquiry |
◆ Lysates | ||
ARHGAP28-112HCL | Recombinant Human ARHGAP28 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (12)
Ask a questionYes, ARHGAP28 has been shown to interact with several proteins involved in Rho GTPase signaling pathways. For example, it can interact with RhoA, Rac1, and Cdc42, suggesting its role in modulating their activities.
It is advisable to consult scientific databases or literature repositories to stay updated on any ongoing research studies or recent publications related to ARHGAP28. These sources will provide accurate and current information on the latest findings regarding ARHGAP28 and its functions.
To the best of my knowledge, there are currently no specific animal models that have been developed to study ARHGAP28. However, researchers may potentially utilize gene knockout or knockdown techniques to study its function in animal models.
Currently, there is no evidence to suggest that ARHGAP28 can be used as a diagnostic or prognostic marker for any diseases. It is important to conduct further research to explore its potential clinical relevance.
ARHGAP28 is widely expressed across different tissues in the body. It has been detected in various cell types, including neurons, epithelial cells, and immune cells.
There is limited information on the involvement of ARHGAP28 in cell migration or invasion. However, given its association with Rho GTPases, which are key regulators of these processes, ARHGAP28 may potentially play a role in cell migration and invasion.
Currently, there are no specific studies linking ARHGAP28 to particular diseases or conditions. Thus, more research is needed to determine its potential involvement in different physiological and pathological processes.
ARHGAP28 has been shown to interact with proteins involved in the Rho GTPase signaling pathway. Additionally, it may localize to cellular structures such as actin-rich filopodia and lamellipodia, which play key roles in cell movement and adhesion.
Currently, there are no known genetic variations or mutations in the ARHGAP28 gene associated with diseases. Further studies are needed to determine if any genetic alterations in this gene have implications for human health.
ARHGAP28 is believed to function as a negative regulator of Rho GTPases, which are involved in several signaling pathways, including those related to actin cytoskeleton organization, cell adhesion, and cell migration. Therefore, ARHGAP28 may indirectly influence these signaling pathways through its modulation of Rho GTPases.
As of now, there are no known drugs or inhibitors specifically targeting ARHGAP28. Further exploration of its function and potential therapeutic implications may reveal novel possibilities for targeted interventions.
There is currently limited information on the relationship between ARHGAP28 and developmental disorders. However, given its involvement in cell motility and morphology, it is plausible that disruptions in ARHGAP28 expression or function could contribute to developmental abnormalities, but more research is needed to establish such connections.
Customer Reviews (10)
Write a reviewI have full confidence in the ARHGAP28 protein and the exceptional support provided by the manufacturer, making it my top recommendation for researchers seeking a high-quality protein for their experimental needs.
Their knowledgeable team has been readily available to address any concerns or queries, providing effective solutions and guidance whenever needed.
Its integrity and reliability make it an ideal choice to address the specific objectives of my research.
I am extremely pleased with the quality of the ARHGAP28 protein as it perfectly fulfills my experimental requirements.
Their ability to accommodate the requirements of large-scale experiments and guarantee a steady supply streamlines my research operations, eliminating any concerns related to prospective shortages.
I am delighted to express my complete satisfaction with the quality of ARHGAP28 protein, as it precisely suits my experimental requirements.
This protein exhibits exceptional purity and reliability, ensuring accurate and reproducible results in my assays.
With their meticulous documentation and support, I am confident that my utilization of the ARHGAP8 protein in clinical trials will meet all necessary regulations and guidelines.
Their comprehensive certificates of analysis and safety data sheets serve as testaments to their commitment to ensuring the safety and integrity of their products.
In addition to the exceptional quality of the protein, the manufacturer's support extends beyond the product itself.
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