Recombinant Full Length Human AS3MT Protein, GST-tagged
Cat.No. : | AS3MT-1256HF |
Product Overview : | Human AS3MT full-length ORF ( AAI60057.1, 1 a.a. - 375 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | AS3MT catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to trivalent arsenical and may play a role in arsenic metabolism (Lin et al., 2002 [PubMed 11790780]).[supplied by OMIM, Mar 2008] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 67.65 kDa |
Protein Length : | 375 amino acids |
AA Sequence : | MAALRDAEIQ KDVQTYYGQV LKRSADLQTN GCVTTARPVP KHIREALQNV HEEVALRYYG CGLVIPEHLE NCWILDLGSG SGRDCYVLSQ LVGEKGHVTG IDMTKGQVEV AEKYLDYHME KYGFQASNVT FIHGYIEKLG EAGIKNESHD IVVSNCVINL VPDKQQVLQE AYRVLKHGGE LYFSDVYTSL ELPEEIRTHK VLWGECLGGA LYWKELAVLA QKIGFCPPRL VTANLITIQN KELERVIGDC RFVSATFRLF KHSKTGPTKR CQVIYNGGIT GHEKELMFDA NFTFKEGEIV EVDEETAAIL KNSRFAQDFL IRPIGEKLPT SGGCSALELK DIITDPFKLA EESDSMKSRC VPDAAGGCCG TKKSC |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | AS3MT arsenic (+3 oxidation state) methyltransferase [ Homo sapiens ] |
Official Symbol : | AS3MT |
Synonyms : | AS3MT; arsenic (+3 oxidation state) methyltransferase; arsenite methyltransferase; CYT19; methyltransferase cyt19; methylarsonite methyltransferase; S-adenosylmethionine:arsenic (III) methyltransferase; S-adenosyl-L-methionine:arsenic(III) methyltransferase; RP11-753C18.6 |
Gene ID : | 57412 |
mRNA Refseq : | NM_020682 |
Protein Refseq : | NP_065733 |
MIM : | 611806 |
UniProt ID : | Q9HBK9 |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionThe AS3MT protein plays a crucial role in the detoxification and elimination of arsenic from the body, preventing its accumulation and potential toxicity.
The AS3MT protein binds to and methylates inorganic arsenic, facilitating its conversion into organic arsenic metabolites that are easier to eliminate from the body.
The AS3MT protein is primarily associated with the metabolism of arsenic and has not been extensively linked to the metabolism of other substances.
Impairment or dysfunction of the AS3MT protein can lead to reduced arsenic methylation ability, potentially increasing arsenic toxicity in the body.
Yes, alterations in AS3MT gene expression can influence the methylation capacity of arsenic, potentially leading to variations in arsenic toxicity levels.
Yes, genetic variations in the AS3MT gene have been identified and can influence the activity and expression of the AS3MT protein.
The AS3MT protein is associated with arsenic-induced diseases and conditions, such as arsenic poisoning, arsenic-related cancers, and cardiovascular diseases.
Customer Reviews (3)
Write a reviewThe AS3MT Protein has exceeded my expectations by consistently delivering outstanding results and providing exceptional technical support.
In addition to its remarkable quality and exceptional technical support, the AS3MT Protein boasts an impressive range of applications.
Their prompt assistance and willingness to go above and beyond to ensure my success have been immensely valuable.
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