Recombinant Full Length Human ASB7 Protein, GST-tagged

• Cat.No.: ASB7-1361HF
• Product Overview: Human ASB7 full-length ORF ( NP_078984.2, 1 a.a. - 274 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 57.1 kDa
• Protein Length: 274 amino acids
• AA Sequence: MLHHHCRRNP ELQEELQIQA AVAAGDVHTV RKMLEQGYSP NGRDANGWTL LHFSAARGKE RCVRVFLEHG ADPTVKDLIG GFTALHYAAM HGRARIARLM LESEYRSDII NAKSNDGWTP LHVAAHYGRD SFVRLLLEFK AEVDPLSDKG TTPLQLAIIR ERSSCVKILL DHNANIDIQN GFLLRYAVIK SNHSYCRMFL QRGADTNLGR LEDGQTPLHL SALRDDVLCA RMLYNYGADT NTRNYEGQTP LAVSISISGS SRPCLDFLQE VTSM
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ASB7 ankyrin repeat and SOCS box containing 7 [ Homo sapiens ]
• Official Symbol: ASB7
• Synonyms: ASB7; ankyrin repeat and SOCS box containing 7; ankyrin repeat and SOCS box protein 7; ASB-7; ankyrin repeat and SOCS box-containing 7; FLJ22551; FLJ25192
• Gene ID: 140460
• mRNA Refseq: NM_024708
• Protein Refseq: NP_078984
• MIM: 615052
• UniProt ID: Q9H672

Reviews

10/04/2016

Should I encounter any challenges or require technical assistance, the manufacturer provides prompt and knowledgeable support.

05/29/2016

Their expertise in protein production and purification ensures the delivery of a high-quality product that consistently performs well in my experiments.

05/27/2016

the manufacturer's commitment to quality control and rigorous testing guarantees the reliability and reproducibility of the ASB7 protein, which is essential for obtaining accurate and consistent results.

Q&As

Are there any known therapeutic implications or potential targets involving ASB7?

Currently, there are no known therapeutic implications specifically related to ASB7. However, exploring its functions and interactions may reveal potential therapeutic targets for certain diseases or conditions.

Are there any known genetic variants or mutations in the ASB7 gene?

Although ASB7 genetic variants may exist, they have not been extensively studied. Further research is required to identify and understand any potential genetic changes in ASB7.

Is the expression of ASB7 regulated by any specific factors or conditions?

The specific factors or conditions that regulate ASB7 expression remain largely unknown. Investigating its expression patterns under different conditions could provide insights into its regulatory mechanisms.

Is there any evidence to suggest a role for ASB7 in cellular metabolism or energy homeostasis?

The involvement of ASB7 in cellular metabolism or energy homeostasis is not well-established. Further research is needed to determine if ASB7 plays a role in these processes.