Recombinant Full Length Human ATF4 Protein, N-His-tagged
Cat.No. : | ATF4-217HFL |
Product Overview : | Recombinant Full Length Human ATF4 Protein, fused to His-tag at N-terminus, was expressed in E. coli. |
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Description : | This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl. |
Molecular Mass : | 38.4 kDa |
AA Sequence : | A DNA sequence encoding human full-length ATF4. |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Protein Families : | Transcription Factors |
Protein Pathways : | GnRH signaling pathway, Long-term potentiation, MAPK signaling pathway, Neurotrophin signaling pathway, Prostate cancer |
Gene Name : | ATF4 activating transcription factor 4 [ Homo sapiens (human) ] |
Official Symbol : | ATF4 |
Synonyms : | CREB2; TXREB; CREB-2; TAXREB67 |
Gene ID : | 468 |
mRNA Refseq : | NM_001675.4 |
Protein Refseq : | NP_001666.2 |
MIM : | 604064 |
UniProt ID : | P18848 |
Products Types
◆ Recombinant Protein | ||
ATF4-3596H | Recombinant Human ATF4, His Cam-tagged | +Inquiry |
ATF4-813M | Recombinant Mouse ATF4 Protein, His (Fc)-Avi-tagged | +Inquiry |
ATF4-267R | Recombinant Rhesus Macaque ATF4 Protein, His (Fc)-Avi-tagged | +Inquiry |
Atf4-183R | Recombinant Rat Atf4 protein, His&Myc-tagged | +Inquiry |
ATF4-939H | Recombinant Human ATF4 protein, GST-tagged | +Inquiry |
◆ Lysates | ||
ATF4-8630HCL | Recombinant Human ATF4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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