Recombinant Full Length Human CAST Protein
Cat.No. : | CAST-50HF |
Product Overview : | Recombinant full length corresponding to amino acids 1-686 of Human Calpastatin with a proprietary tag; predicited MWt 101.3kDa inclusive of tag. |
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Description : | The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. |
Source : | In Vitro Cell Free System |
Species : | Human |
Form : | Liquid |
Molecular Mass : | 101.530kDa inclusive of tags |
Protein Length : | 686 amino acids |
AA Sequence : | MNPTETKAVK TEPEKKSQST KLSVVHEKKS QEGKPKEHTE PKSLPKQASD TGSNDAHNKK AVSRSAEQQP SEKSTEPKTK PQDMISAGGE SVAGITAISG KPGDKKKEKK SLTPAVPVES KPDKPSGKSG MDAALDDLID TLGGPEETEE ENTTYTGPEV SDPMSSTYIE ELGKREVTIP PKYRELLAKK EGITGPPADS SKPIGPDDAI DALSSDFTCG SPTAAGKKTE KEESTEVLKA QSAGTVRSAA PPQEKKRKVE KDTMSDQALE ALSASLGTRQ AEPELDLRSI KEVDEAKAKE EKLEKCGEDD ETIPSEYRLK PATDKDGKPL LPEPEEKPKP RSESELIDEL SEDFDRSECK EKPSKPTEKT EESKAAAPAP VSEAVCRTSM CSIQSAPPEP ATLKGTVPDD AVEALADSLG KKEADPEDGK PVMDKVKEKA KEEDREKLGE KEETIPPDYR LEEVKDKDGK PLLPKESKEQ LPPMSEDFLL DALSEDFSGP QNASSLKFED AKLAAAISEV VSQTPASTTQ AGAPPRDTSQ SDKDLDDALD KLSDSLGQRQ PDPDENKPME DKVKEKAKAE HRDKLGERDD TIPPEYRHLL DDNGQDKPVK PPTKKSEDSK KPADDQDPID ALSGDLDSCP STTETSQNTA KDKCKKAASS SKAPKNGGKA KDSAKTTEET SKPKDD |
Purity : | Proprietary Purification |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles. |
Storage Buffer : | pH: 8.00. Constituents: 0.3% Glutathione, 0.79% Tris HCl. |
Gene Name : | CAST calpastatin [ Homo sapiens ] |
Official Symbol : | CAST |
Synonyms : | CAST; calpastatin |
Gene ID : | 831 |
mRNA Refseq : | NM_001042440 |
Protein Refseq : | NP_001035905 |
MIM : | 114090 |
UniProt ID : | P20810 |
Products Types
◆ Recombinant Protein | ||
CAST-1350H | Recombinant Human CAST Protein (1-667 aa), His-tagged | +Inquiry |
CAST-0441H | Recombinant Human CAST Protein, GST-Tagged | +Inquiry |
CAST-628H | Recombinant Human CAST Protein, His&GST-tagged | +Inquiry |
Cast-776M | Recombinant Mouse Cast Protein, MYC/DDK-tagged | +Inquiry |
CAST-807R | Recombinant Rat CAST Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CAST-7824HCL | Recombinant Human CAST 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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