Recombinant Full Length Human CDK8, Flag-tagged
Cat.No. : | CDK8-1603HFL |
Product Overview : | Recombinant Full Length Human CDK8, fused with C-terminal Flag tag, was expressed in mamanlian cells. |
- Specification
- Gene Information
- Related Products
- Download
Source : | Mamanlian cells |
Species : | Human |
Tag : | Flag |
Molecular Mass : | 53.1 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Storage : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Shipping : | The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below. |
Gene Name : | CDK8 cyclin-dependent kinase 8 [ Homo sapiens (human) ] |
Official Symbol : | CDK8 |
Synonyms : | cyclin-dependent kinase 8; K35; MGC126074; MGC126075; protein kinase K35; CDK8 protein kinase; cell division protein kinase 8; EC 2.7.11.22,EC 2.7.11.23; Protein kinase K35; CDK8; OTTHUMP00000018158; Mediator complex subunit CDK8; Mediator of RNA polymerase II transcription subunit CDK8 |
Gene ID : | 1024 |
mRNA Refseq : | NM_001260 |
Protein Refseq : | NP_001251 |
MIM : | 603184 |
UniProt ID : | P49336 |
Products Types
◆ Recombinant Protein | ||
CDK8-1038H | Active Recombinant Human CDK8 Protein, GST-Tagged | +Inquiry |
Cdk8-2091M | Recombinant Mouse Cdk8 Protein, Myc/DDK-tagged | +Inquiry |
CDK8-1039H | Active Recombinant Human CDK8 Protein, His-Tagged | +Inquiry |
CDK8-1531M | Recombinant Mouse CDK8 Protein, His (Fc)-Avi-tagged | +Inquiry |
CDK8-616R | Recombinant Rhesus Macaque CDK8 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CDK8-7620HCL | Recombinant Human CDK8 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionCDK8 plays essential roles in normal cellular functions, including development and tissue homeostasis. Its dysregulation, however, is implicated in cancer.
Combination therapies involving CDK8 inhibitors are being explored to enhance treatment outcomes and reduce the likelihood of resistance, providing a more comprehensive approach to cancer management.
CDK8 inhibition can disrupt the cell cycle, slowing down or halting the uncontrolled cell division characteristic of cancer cells, making it a potential therapeutic strategy.
CDK8 can modulate the expression of genes involved in immune response. Understanding its role in the tumor microenvironment may lead to novel immunotherapeutic strategies.
Yes, several clinical trials are underway to assess the safety and effectiveness of CDK8 inhibitors as a targeted therapy for different types of cancer.
Customer Reviews (3)
Write a reviewThe CDK8 protein stands as a remarkable solution that exemplifies exceptional quality and meets all my experimental requirements.
I am confident that the CDK8 protein will unlock vital insights into cellular processes, propelling my scientific investigations to new heights.
Its impressive purity and functional characteristics make it an ideal choice for my research endeavors, ensuring reliable and impactful results.
Ask a Question for All CDK8 Products
Required fields are marked with *
My Review for All CDK8 Products
Required fields are marked with *
Inquiry Basket