Recombinant Full Length Human DNM2, Flag-tagged

• Cat.No.: DNM2-6495HFL
• Product Overview: Recombinant Full Length Human DNM2, fused with C-terminal Flag tag, was expressed in mamanlian cells.

Specification

• Source: Mamanlian cells
• Species: Human
• Tag: Flag
• Molecular Mass: 97.5 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Storage: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Concentration: >50 ug/mL as determined by microplate BCA method
• Shipping: The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Gene Information

• Gene Name: DNM2 dynamin 2 [ Homo sapiens ]
• Official Symbol: DNM2
• Synonyms: DNM2; DYN2; CMT2M; DYNII; LCCS5; CMTDI1; CMTDIB; DI-CMTB; dynamin 2; dynamin-2; dynamin II; NP_001005360.1; EC 3.6.5.5; NP_001005361.1; NP_001005362.1; NP_001177645.1; NP_004936.2
• Gene ID: 1785
• mRNA Refseq: NM_004945
• Protein Refseq: NP_004936
• MIM: 602378
• UniProt ID: P50570

Reviews

03/02/2023

DNM2 proteins purchased are as advertised and the quality of the product is guaranteed.

08/16/2022

Excellent after-sales service, solving many experimental problems.

03/12/2022

The technician gave me a thorough introduction to the DNM2 protein so that I could understand its biochemical properties.

Q&As

What is the relationship between DNM2 and β-actin?

DNM2 interacts with β-actin.

What diseases is DNM2 primarily involved in?

DNM2 is closely associated with the study of chronic heart failure and chronic progressive extraocular muscle paralysis in the elderly.

Where is DNM2 primarily expressed?

DNM2 gene is widely expressed in various mammalian tissues.

What are the other homologous genes of DNM2?

DNM1 and DNM3 are all homologs of DNM2.

What biological processes is DNM2 involved in?

DNM2 is involved in the regulation of Golgi reticular system transport, mitochondrial fusion, cytoplasmic division and synaptic vesicle endocytosis.

What is the structure domain of DNM2?

N-terminal GTPase structural domain, intermediate domain, PH structural domain, GTPase effector structural domain, and C-terminal proline- and arginine-rich domain.