Recombinant Full Length Human FABP1 Protein, GST-tagged

• Cat.No.: FABP1-4420HF
• Product Overview: Human FABP1 full-length ORF ( AAH32801, 1 a.a. - 127 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. This protein and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Mar 2011]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 39.71 kDa
• Protein Length: 127 amino acids
• AA Sequence: MSFSGKYQLQSQENFEAFMKAIGLP EELIQKGKDIKGVSEIVQNGKHFKF TITAGSKVIQNEFTVGEECELETMT GEKVKTVVQLEGDNKLVTTFKNIKS VTELNGDIITNTMTLGDIVFKRISK RI
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FABP1 fatty acid binding protein 1, liver [ Homo sapiens ]
• Official Symbol: FABP1
• Synonyms: FABP1; fatty acid binding protein 1, liver; fatty acid-binding protein, liver; L FABP; fatty acid-binding protein 1; liver-type fatty acid-binding protein; FABPL; L-FABP
• Gene ID: 2168
• mRNA Refseq: NM_001443
• Protein Refseq: NP_001434
• MIM: 134650
• UniProt ID: P07148

Reviews

07/24/2019

One notable advantage of using the FABP1 protein is the outstanding technical support provided by its manufacturer.

05/28/2019

Its purity and functionality have been extensively tested, ensuring reliable and reproducible results in my research.

05/22/2019

The knowledgeable and responsive support team offers valuable assistance and expertise, making troubleshooting and problem-solving much more efficient.

Q&As

How is FABP1 linked to metabolic disorders?

Elevated levels of FABP1 are associated with metabolic disorders like obesity and insulin resistance, making it a potential indicator for these conditions.

How is FABP1 involved in fatty acid metabolism?

FABP1 binds to fatty acids, facilitating their transport and metabolism within liver cells.

Are there other organs where FABP1 is expressed?

While predominantly found in the liver, FABP1 is also expressed in the small intestine and kidney.

Can FABP1 be used for early detection of liver damage?

Yes, elevated FABP1 levels in blood or urine may indicate early stages of liver damage, enabling early intervention.

Are there genetic variations influencing FABP1 expression?

Genetic variations may contribute to differences in FABP1 expression, impacting an individual's susceptibility to certain diseases.