Recombinant Full Length Human HLA-E Protein, C-Flag-tagged
Cat.No. : | HLA-E-268HFL |
Product Overview : | Recombinant Full Length Human HLA-E Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 37.8 kDa |
AA Sequence : | MVDGTLLLLLSEALALTQTWAGSHS LKYFHTSVSRPGRGEPRFISVGYVD DTQFVRFDNDAASPRMVPRA PWMEQEGSEYWDRETRSARDTAQIF RVNLRTLRGYYNQSEAGSHTLQWMH GCELGPDGRFLRGYEQFAYD GKDYLTLNEDLRSWTAVDTAAQISE QKSNDASEAEHQRAYLEDTCVEWLH KYLEKGKETLLHLEPPKTHV THHPISDHEATLRCWALGFYPAEIT LTWQQDGEGHTQDTELVETRPAGDG TFQKWAAVVVPSGEEQRYTC HVQHEGLPEPVTLRWKPASQPTIPI VGIIAGLVLLGSVVSGAVVAAVIWR KKSSGGKGGSYSKAEWSDSA QGSESHSLTRTRPLEQKLISEEDLA ANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Transmembrane |
Protein Pathways : | Allograft rejection, Antigen processing and presentation, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Endocytosis, Graft-versus-host disease, Natural killer cell mediated cytotoxicity, Type I diabetes mellitus, Viral myocarditis |
Gene Name : | HLA-E major histocompatibility complex, class I, E [ Homo sapiens (human) ] |
Official Symbol : | HLA-E |
Synonyms : | QA1; HLA-6.2 |
Gene ID : | 3133 |
mRNA Refseq : | NM_005516.6 |
Protein Refseq : | NP_005507.3 |
MIM : | 143010 |
UniProt ID : | P13747 |
Products Types
◆ Recombinant Protein | ||
HLA-E-1749H | Recombinant Human HLA-E Protein, MYC/DDK-tagged | +Inquiry |
HLA-E-4847H | Recombinant Human HLA-E Protein, GST-tagged | +Inquiry |
HLA-E-1076H | Recombinant Human HLA-E Protein, His (Fc)-Avi-tagged | +Inquiry |
HLA-E-039H | Recombinant Human HLA-E protein, His-Avi-tagged, Biotinylated | +Inquiry |
HLA-E-3399H | Recombinant Human HLA-E protein, His-tagged | +Inquiry |
◆ Lysates | ||
HLA-E-800HCL | Recombinant Human HLA-E cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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