Recombinant Full Length Human IFNG Protein, C-Flag-tagged

• Cat.No.: IFNG-72HFL
• Product Overview: Recombinant Full Length Human IFNG Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 16.7 kDa
• AA Sequence: MKYTSYILAFQLCIVLGSLGCYCQD PYVKEAENLKKYFNAGHSDVADNGT LFLGILKNWKEESDRKIMQS QIVSFYFKLFKNFKDDQSIQKSVET IKEDMNVKFFNSNKKKRDDFEKLTN YSVTDLNVQRKAIHELIQVM
  AELSPAAKTGKRKRSQMLFRGRRAS QTRTRPLEQKLISEEDLAANDILDY KDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Allograft rejection, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Proteasome, Regulation of autophagy, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Type I diabetes mellitus

Gene Information

• Gene Name: IFNG interferon gamma [ Homo sapiens (human) ]
• Official Symbol: IFNG
• Synonyms: IFG; IFI; IMD69
• Gene ID: 3458
• mRNA Refseq: NM_000619.3
• Protein Refseq: NP_000610.2
• MIM: 147570
• UniProt ID: P01579