Recombinant Full Length Human IGFBP2 Protein, C-Flag-tagged

• Cat.No.: IGFBP2-1059HFL
• Product Overview: Recombinant Full Length Human IGFBP2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is one of six similar proteins that bind insulin-like growth factors I and II (IGF-I and IGF-II). The encoded protein can be secreted into the bloodstream, where it binds IGF-I and IGF-II with high affinity, or it can remain intracellular, interacting with many different ligands. High expression levels of this protein promote the growth of several types of tumors and may be predictive of the chances of recovery of the patient. Several transcript variants, one encoding a secreted isoform and the others encoding nonsecreted isoforms, have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 35 kDa
• AA Sequence: MLPRVGCPALPLPPPPLLPLLPLLL LLLGASGGGGGARAEVLFRCPPCTP ERLAACGPPPVAPPAAVAAV AGGARMPCAELVREPGCGCCSVCAR LEGEACGVYTPRCGQGLRCYPHPGS ELPLQALVMGEGTCEKRRDA EYGASPEQVADNGDDHSEGGLVENH VDSTMNMLGGGGSAGRKPLKSGMKE LAVFREKVTEQHRQMGKGGK HHLGLEEPKKLRPPPARTPCQQELD QVLERISTMRLPDERGPLEHLYSLH IPNCDKHGLYNLKQCKMSLN
  GQRGECWCVNPNTGKLIQGAPTIRG DPECHLFYNEQQEARGVHTQRMQTR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Pathways: Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Secreted Protein

Gene Information

• Gene Name: IGFBP2 insulin like growth factor binding protein 2 [ Homo sapiens (human) ]
• Official Symbol: IGFBP2
• Synonyms: IBP2; IGF-BP53
• Gene ID: 3485
• mRNA Refseq: NM_000597.3
• Protein Refseq: NP_000588.3
• MIM: 146731
• UniProt ID: P18065