Recombinant Full Length Human ILF3 Protein, C-Flag-tagged

• Cat.No.: ILF3-1129HFL
• Product Overview: Recombinant Full Length Human ILF3 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 95.2 kDa
• AA Sequence: MRIFVNDDRHVMAKHSSVYPTQEEL EAVQNMVSHTERALKAVSDWIDEQE KGSSEQAESDNMDVPPEDDS KEGAGEQKTEHMTRTLRGVMRVGLV AKGLLLKGDLDLELVLLCKEKPTTA LLDKVADNLAIQLAAVTEDK YEILQSVDDAAIVIKNTKEPPLSLT IHLTSPVVREEMEKVLAGETLSVND PPDVLDRQKCLAALASLRHA KWFQARANGLKSCVIVIRVLRDLCT RVPTWGPLRGWPLELLCEKSIGTAN RPMGAGEALRRVLECLASGI VMPDGSGIYDPCEKEATDAIGHLDR QQREDITQSAQHALRLAAFGQLHKV LGMDPLPSKMPKKPKNENPV DYTVQIPPSTTYAITPMKRPMEEDG EEKSPSKKKKKIQKKEEKAEPPQAM NALMRLNQLKPGLQYKLVSQ TGPVHAPIFTMSVEVDGNSFEASGP SKKTAKLHVAVKVLQDMGLPTGAEG RDSSKGEDSAEETEAKPAVV APAPVVEAVSTPSAAFPSDATAEQG PILTKHGKNPVMELNEKRRGLKYEL ISETGGSHDKRFVMEVEVDG QKFQGAGSNKKVAKAYAALAALEKL FPDTPLALDANKKKRAPVPVRGGPK FAAKPHNPGFGMGGPMHNEV PPPPNLRGRGRGGSIRGRGRGRGFG GANHGGYMNAGAGYGSYGYGGNSAT AGYSQFYSNGGHSGNASGGG GGGGGGSSGYGSYYQGDNYNSPVPP KHAGKKQPHGGQQKPSYGSGYQSHQ GQQQSYNQSPYSNYGPPQGK QKGYNHGQGSYSYSNSYNSPGGGGG SDYNYESKFNYSGSGGRSGGNSYGS GGASYNPGSHGGYGGGSGGG
  SSYQGKQGGYSQSNYNSPGSGQNYS GPPSSYQSSQGGYGRNADHSMNYQY RTRTRPLEQKLISEEDLAANDILDY KDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transcription Factors

Gene Information

• Gene Name: ILF3 interleukin enhancer binding factor 3 [ Homo sapiens (human) ]
• Official Symbol: ILF3
• Synonyms: CBTF; DRBF; MMP4; MPP4; NF90; NFAR; NF110; NF90a; NF90b; NF90c; NFAR2; TCP80; DRBP76; NF110b; NFAR-1; NFAR-2; NFAR90; TCP110; MPP4110; NF90ctv; NFAR110; MPHOSPH4; NF-AT-90
• Gene ID: 3609
• mRNA Refseq: NM_012218.4
• Protein Refseq: NP_036350.2
• MIM: 603182
• UniProt ID: Q12906

Reviews

07/17/2022

The impurities are not obvious, clear and transparent, and the purity is high.

07/13/2022

It can meet the needs of daily experiments, and the expression effect is good.

02/27/2021

ILF3 has performed well in experiments and is a reliable choice.

Q&As

Which tumors are associated with ILF3? What role does it play in tumor development?

This is associated with a variety of tumors, including breast cancer, lung cancer, and colon cancer. In tumor development, ILF3 may promote cell proliferation, apoptosis inhibition, and metastasis.

What progress has been made in the exploration of new methods and new drugs for ILF3 treatment of tumors?

At present for ILF3 new treatment for cancer and new drug exploration is still in its infancy, but some ILF3 related drugs and treatment strategies are in development and evaluation, bring new hope for patients.

Is ILF3 associated with tumor microenvironment and immune escape?

This peotein may be associated with tumor microenvironment and immune escape, and can regulate the interaction between tumor cells and immune cells, further deepening our understanding of the mechanism of immune escape.

Is there a relationship between LF3 and tumor prognosis and treatment response?

The association between ILF3 and tumor prognosis and treatment response needs to be further studied, but according to the current study, high expression of ILF3 may be associated with poor prognosis and drug resistance in cancer patients.

What are the functions and mechanisms of ILF3 in infectious diseases?

ILF3 may play an important immunomodulatory function in infectious diseases and may be involved in the immune response and inflammatory response caused by viral or bacterial infection.

What is ILF3 role in autoimmune diseases? What autoimmune diseases might it be involved in?

It may play an important role in autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus (sle), may be involved in these diseases by means of immune regulation of occurrence and development.