Recombinant Full Length Human INSRR Protein, C-Flag-tagged

• Cat.No.: INSRR-1942HFL
• Product Overview: Recombinant Full Length Human INSRR Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Enables transmembrane receptor protein tyrosine kinase activity. Involved in actin cytoskeleton reorganization; cellular response to alkaline pH; and protein autophosphorylation. Part of receptor complex.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 140.9 kDa
• AA Sequence: MAVPSLWPWGACLPVIFLSLGFGLD TVEVCPSLDIRSEVAELRQLENCSV VEGHLQILLMFTATGEDFRG LSFPRLTQVTDYLLLFRVYGLESLR DLFPNLAVIRGTRLFLGYALVIFEM PHLRDVALPALGAVLRGAVR VEKNQELCHLSTIDWGLLQPAPGAN HIVGNKLGEECADVCPGVLGAAGEP CAKTTFSGHTDYRCWTSSHC QRVCPCPHGMACTARGECCHTECLG GCSQPEDPRACVACRHLYFQGACLW ACPPGTYQYESWRCVTAERC ASLHSVPGRASTFGIHQGSCLAQCP SGFTRNSSSIFCHKCEGLCPKECKV GTKTIDSIQAAQDLVGCTHV EGSLILNLRQGYNLEPQLQHSLGLV ETITGFLKIKHSFALVSLGFFKNLK LIRGDAMVDGNYTLYVLDNQ NLQQLGSWVAAGLTIPVGKIYFAFN PRLCLEHIYRLEEVTGTRGRQNKAE INPRTNGDRAACQTRTLRFV SNVTEADRILLRWERYEPLEARDLL SFIVYYKESPFQNATEHVGPDACGT QSWNLLDVELPLSRTQEPGV TLASLKPWTQYAVFVRAITLTTEED SPHQGAQSPIVYLRTLPAAPTVPQD VISTSNSSSHLLVRWKPPTQ RNGNLTYYLVLWQRLAEDGDLYLND YCHRGLRLPTSNNDPRFDGEDGDPE AEMESDCCPCQHPPPGQVLP PLEAQEASFQKKFENFLHNAITIPI SPWKVTSINKSPQRDSGRHRRAAGP LRLGGNSSDFEIQEDKVPRE RAVLSGLRHFTEYRIDIHACNHAAH TVGCSAATFVFARTMPHREADGIPG KVAWEASSKNSVLLRWLEPP DPNGLILKYEIKYRRLGEEATVLCV SRLRYAKFGGVHLALLPPGNYSARV RATSLAGNGSWTDSVAFYIL GPEEEDAGGLHVLLTATPVGLTLLI VLAALGFFYGKKRNRTLYASVNPEY FSASDMYVPDEWEVPREQIS IIRELGQGSFGMVYEGLARGLEAGE ESTPVALKTVNELASPRECIEFLKE ASVMKAFKCHHVVRLLGVVS QGQPTLVIMELMTRGDLKSHLRSLR PEAENNPGLPQPALGEMIQMAGEIA DGMAYLAANKFVHRDLAARN CMVSQDFTVKIGDFGMTRDVYETDY YRKGGKGLLPVRWMAPESLKDGIFT THSDVWSFGVVLWEIVTLAE QPYQGLSNEQVLKFVMDGGVLEELE GCPLQLQELMSRCWQPNPRLRPSFT HILDSIQEELRPSFRLLSFY YSPECRGARGSLPTTDAEPDSSPTP RDCSPQNGGPGH TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Protein Pathways: Prostate cancer, Regulation of actin cytoskeleton

Gene Information

• Gene Name: INSRR insulin receptor related receptor [ Homo sapiens (human) ]
• Official Symbol: INSRR
• Synonyms: IRR
• Gene ID: 3645
• mRNA Refseq: NM_014215.3
• Protein Refseq: NP_055030.1
• MIM: 147671
• UniProt ID: P14616