Recombinant Full Length Human Insulin-Induced Gene 2 Protein(Insig2) Protein, His&Myc-Tagged
Cat.No. : | RFL24215HF |
Product Overview : | Recombinant Full Length Human Insulin-induced gene 2 protein(INSIG2) Protein (Q9Y5U4) (1-225aa), fused to N-terminal 10xHis tag and C-terminal Myc tag, was expressed in E. coli. |
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Source : | E.coli expression system |
Species : | Homo sapiens (Human) |
Tag : | His&Myc |
Form : | Lyophilized powder |
Protein Length : | Full Length (1-225aa) |
AA Sequence : | MAEGETESPGPKKCGPYISSVTSQS VNLMIRGVVLFFIGVFLALVLNLLQ IQRNVTLFPPDVIASIFSSAWWVPP CCGTASAVIGLLYPCIDRHLGEPHK FKREWSSVMRCVAVFVGINHASAKV DFDNNIQLSLTLAALSIGLWWTFDR SRSGFGLGVGIAFLATVVTQLLVYN GVYQYTSPDFLYVRSWLPCIFFAGG ITMGNIGRQLAMYECKVIAEKSHQE Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request. |
Purity : | Greater than 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
Storage : | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Tris/PBS-based buffer, 6% Trehalose, pH 8.0 |
Reconstitution : | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference. |
Gene Name : | INSIG2 |
Synonyms : | INSIG2; Insulin-induced gene 2 protein; INSIG-2 |
UniProt ID : | Q9Y5U4 |
Gene Name : | INSIG2 |
Synonyms : | INSIG2; Insulin-induced gene 2 protein; INSIG-2 |
UniProt ID : | Q9Y5U4 |
Products Types
◆ Recombinant Protein | ||
INSIG2-5098H | Recombinant Human INSIG2 Protein, GST-tagged | +Inquiry |
INSIG2-2100R | Recombinant Rhesus Macaque INSIG2 Protein, His (Fc)-Avi-tagged | +Inquiry |
INSIG2-2735R | Recombinant Rat INSIG2 Protein, His (Fc)-Avi-tagged | +Inquiry |
INSIG2-1188H | Recombinant Human INSIG2 Protein, His (Fc)-Avi-tagged | +Inquiry |
INSIG2-2820H | Recombinant Human INSIG2 Protein, His-tagged, OVA Conjugated | +Inquiry |
◆ Lysates | ||
INSIG2-5192HCL | Recombinant Human INSIG2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionWhile specific post-translational modifications may exist, the current literature provides limited information on post-translational regulation of INSIG2.
INSIG2 contributes to insulin sensitivity by regulating lipid metabolism and insulin signaling pathways.
INSIG2 inhibits the activity of both SREBP-1 and SREBP-2, impacting lipogenesis and cholesterol biosynthesis.
INSIG2 is a key regulator of cholesterol synthesis, modulating the activation of SREBP-2, a master regulator of cholesterol biosynthesis.
INSIG2 is involved in the cellular response to ER stress, playing a role in maintaining ER homeostasis.
There is evidence linking INSIG2 to cancer development, suggesting a potential role in tumorigenesis.
Yes, INSIG2 expression can vary in response to different dietary conditions, reflecting its role in metabolic adaptation.
Customer Reviews (3)
Write a reviewWe observed that results obtained with the product remained stable and reliable over long-term experiments.
The product's impact extended to data analysis, with intuitive tools for interpreting experimental results.
Its adaptability to various sample types and conditions made it a valuable asset for our diverse projects.
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