Recombinant Full Length Human MCM7 Protein, C-Flag-tagged
Cat.No. : | MCM7-663HFL |
Product Overview : | Recombinant Full Length Human MCM7 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 81.1 kDa |
AA Sequence : | MALKDYALEKEKVKKFLQEFYQDDE LGKKQFKYGNQLVRLAHREQVALYV DLDDVAEDDPELVDSICENA RRYAKLFADAVQELLPQYKEREVVN KDVLDVYIEHRLMMEQRSRDPGMVR SPQNQYPAELMRRFELYFQG PSSNKPRVIREVRADSVGKLVTVRG IVTRVSEVKPKMVVATYTCDQCGAE TYQPIQSPTFMPLIMCPSQE CQTNRSGGRLYLQTRGSRFIKFQEM KMQEHSDQVPVGNIPRSITVLVEGE NTRIAQPGDHVSVTGIFLPI LRTGFRQVVQGLLSETYLEAHRIVK MNKSEDDESGAGELTREELRQIAEE DFYEKLAASIAPEIYGHEDV KKALLLLLVGGVDQSPRGMKIRGNI NICLMGDPGVAKSQLLSYIDRLAPR SQYTTGRGSSGVGLTAAVLR DSVSGELTLEGGALVLADQGVCCID EFDKMAEADRTAIHEVMEQQTISIA KAGILTTLNARCSILAAANP AYGRYNPRRSLEQNIQLPAALLSRF DLLWLIQDRPDRDNDLRLAQHITYV HQHSRQPPSQFEPLDMKLMR RYIAMCREKQPMVPESLADYITAAY VEMRREAWASKDATYTSARTLLAIL RLSTALARLRMVDVVEKEDV NEAIRLMEMSKDSLLGDKGQTARTQ RPADVIFATVRELVSGGRSVRFSEA EQRCVSRGFTPAQFQAALDE YEELNVWQVNASRTRITFVTRTRPL EQKLISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Transcription Factors |
Protein Pathways : | Cell cycle, DNA replication |
Gene Name : | MCM7 minichromosome maintenance complex component 7 [ Homo sapiens (human) ] |
Official Symbol : | MCM7 |
Synonyms : | MCM2; CDC47; P85MCM; P1CDC47; PNAS146; PPP1R104; P1.1-MCM3 |
Gene ID : | 4176 |
mRNA Refseq : | NM_005916.5 |
Protein Refseq : | NP_005907.3 |
MIM : | 600592 |
UniProt ID : | P33993 |
Products Types
◆ Recombinant Protein | ||
MCM7-4517H | Recombinant Human MCM7 Protein, GST-tagged | +Inquiry |
MCM7-01H | Recombinant Human MCM7 Protein, Myc/DDK-tagged | +Inquiry |
MCM7-1383H | Recombinant Human MCM7 Protein, His (Fc)-Avi-tagged | +Inquiry |
Mcm7-3998M | Recombinant Mouse Mcm7 Protein, Myc/DDK-tagged | +Inquiry |
MCM7-28043TH | Recombinant Human MCM7 | +Inquiry |
◆ Lysates | ||
MCM7-4415HCL | Recombinant Human MCM7 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket