Recombinant Full Length Human MICA Protein, C-Flag-tagged
Cat.No. : | MICA-746HFL |
Product Overview : | Recombinant Full Length Human MICA Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 38.3 kDa |
AA Sequence : | MGLGPVFLLLAGIFPFAPPGAAAEP HSLRYNLTVLSWDGSVQSGFLAEVH LDGQPFLRYDRQKCRAKPQG QWAEDVLGNKTWDRETRDLTGNGKD LRMTLAHIKDQKEGLHSLQEIRVCE IHEDNSTRSSQHFYYDGELF LSQNLETEEWTVPQSSRAQTLAMNV RNFLKEDAMKTKTHYHAMHADCLQE LRRYLESGVVLRRTVPPMVN VTRSEASEGNITVTCRASSFYPRNI ILTWRQDGVSLSHDTQQWGDVLPDG NGTYQTWVATRICRGEEQRF TCYMEHSGNHSTHPVPSGKVLVLQS HWQTFHVSAVAAGCCYFCYYYFLCP LLTRTRPLEQKLISEEDLAANDILD YKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Gene Name : | MICA MHC class I polypeptide-related sequence A [ Homo sapiens (human) ] |
Official Symbol : | MICA |
Synonyms : | MIC-A; PERB11.1 |
Gene ID : | 100507436 |
mRNA Refseq : | NM_001177519.3 |
Protein Refseq : | NP_001170990.1 |
MIM : | 600169 |
UniProt ID : | Q96QC4 |
Products Types
◆ Recombinant Protein | ||
MICA-1778H | Recombinant Human MICA Protein, His&GST-tagged | +Inquiry |
MICA-5319H | Recombinant Human MICA Protein, GST-tagged | +Inquiry |
MICA-401C | Recombinant Cynomolgus MICA Protein, His-tagged | +Inquiry |
MICA-03H | Active Recombinant Human MICA Protein, His-tagged | +Inquiry |
MICA-1232H | Recombinant Human MICA Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
MICA-1941HCL | Recombinant Human MICA cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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