Recombinant Full length Human MUC5AC Protein, C-MYC/DDK-tagged

• Cat.No.: MUC5AC-12HFL
• Product Overview: Recombinant Full Length Human MUC5AC Protein, fused to Myc-DDK-tag at C-terminus, was expressed in HEK293T cells.

Specification

• Description: Predicted to be an extracellular matrix structural constituent. Involved in phosphatidylinositol-mediated signaling. Located in cytoplasm; extracellular space; and mucus layer. Implicated in dry eye syndrome. Biomarker of several diseases, including Sjogren's syndrome; biliary tract disease (multiple); cystic fibrosis; eye disease (multiple); and pancreatic cancer (multiple).
• Source: HEK293
• Species: Human
• Tag: Myc-DDK
• Form: 25mM Tris-HCl, pH7.3, 100mM glycine, 10% glycerol.
• Molecular Mass: 298.9 kDa
• AA Sequence: MGVGRRKLVPFWVLALALACSQCTG QAQQDSLKSYHEHRSDVPHPQGHVG TPLNRVTIIPPLKTIPVVRA FNPGHTRRVCSTWGNFHYKTFDGQV FYFPGLCNYVFSAHCGDAYEDFNIQ LRRVQESNTTTLSRVTMKLD GLVVELTKSSVLVNNHPVQLPFSQS GVLIELSNGYLKVVARLGLLFVWNE DDSLLLELDTKYTNKTCGLC GDFNGSPKSNEFLSNNVRLTPLEFG NLQKMDGPTEQCQDPLPVPQKNCSA RSGICEMILKGELFSGCAAL VDISSYVEACRQDVCLCESLDPSDC ICHTLAEYSRQCAHAGGQPQDWRGP NLCSQTCPLNMQHQECGSPC VDTCSNPQHSQVCEDHCIAGCFCPE GMVLDDINQMGCVPVSQCACLYNGT LYAPGTNYSTDCTNTCSGGQ WSCQDIPCAGTCSVMGGSHMSTFDG RQYTVHGDCTYVLSKPCDSNAFTVL VELRKCGLTESETCLKTVTL NLGGGQTEIMVKATGEVFVNQIYTQ LPVSTANATFFRPSTFFIVGETNLG LQLEIQLSPIMQTSVRLKPG LRGLTCGLCGNFNSMQADDFQTISG VVEGTAAAFFNTFKTQAACPNVKNI FQDPCSLSVENEKYAQHWCS LLTNASGPFSQCHATVNPSTFFSNC MYDTCNCEKSEDCMCAALSSYVRAC AAKGVLLSDWRDGICTKPTI TCPKSMTYQYHISTCQPTCRALNEK DVTCHVSFIPVDGCTCPKGTFLDDL GKCVQATSCPCYYKGSTVPN GESVQDSGAICTCTQGALTCIGGPA PTPVCDAPMIYFDCHNATPGDTGAG CQKSCHTLDMTCYSSECVPG CVCPNGLVADGNGGCVVTEDCPCVH NEATYRPGETIQVGCNNCTCENRMW QCTDKPCLATCAVYGDGHYI TFDGQRYSFNGDCEYTLLQDNCGGN GSSQDAFRVITENIPCGTTGTTCSK SIKIFLGNYELKLSDSKMEV VQKDVGQEPPYFVHQMGNYLVVETD IGLVLLWDKKTSIFLRLSPEFKGRV CGLCGNFDDNAINDFTTRSQ SVVSDMLEFGNSWKLSPSCPDVLVP KDPCTANPYRKSWAQKQCSIINSET FSACHAHVEPAKYYEACVND ACACDSGGDCECFCTTVAAYAQACH EVGVCVSWRTPDICPLFCDYYNPEG QCEWHYQPCGAPCMRTCQNP TGQCLQDLRGLEGCYPKCPPTAPIF DEGTMQCVSNCTVTFPCRVNGKLYR PGASVPSDKNCDSCICTESG VRCTHNAGACVCTYNGQQFHPGEII YHTTDGIGGCISAHCRANGTIERSV DTCNSTTPTPPTTFSFSTPP VMTSMQPSSTHSSPTPSVGSSGASS KAASTTSSILSVKSPVTAPMTMSTS ASAVTTSGCREECLWSPWMD VSRPGRGIDSGDFDTLENLRAHGYP ICQVPKAVECRAEASPGVPLPELQQ HLECSTTVGLICYNSDQLSG LCDNYQIKVQCCTPVSCPTSQTTHV ISSSRTTNLDNTTSSVPVTSTEHPY SSTVTSGSSTHTPGLSPSSS VPSSPTPASSTPAPVSSTTVKTTLP ITSPTPEPTPAISSVSISTSGSTMP SSETTHECKQELCNWTNWLD GSYPGSGRNSGDFDTFVNLRSKGYK FCEKPRNVECRAQFFPNTPLEELGQ NVTCSREEGLICLNKNQLPP MCYNYEIRIECCTVVNNCSTASVTT HPTSHGVSTKTETNWTTHVYSSPTK DTSSHSATIDTKTWTSGISH TTTQPVTTHCQLQCNWTKWFDTDFP VPGPHGGDLETYSNIERSGERLCHR EEITQLQCRAKNYPEREMED LGQVVKCDPSVGLVCNNRDQGGDSG MCLNYEVRLLCCHIPEDCPRTDQTS PVTLSHKPSSAVVSPSSVSP SLSTSHRVHSTTPCFCSVSGQLYPL GSIIYNQTDLDGHCYYAMCSQDCQV VKRVSQDCPSTMPPPATTLS TSTTPPVTGRDRCNVFPPRLRGETW PMPNCSQATCEGNNVISLSPRQCPE LNEPSCANGYPPLKVDDQDG CCQHYQCQCVCSGWGDPHYITFDGT YYTFLDNCTYVLVQQIVPVFGYFRV LIDNYYCDVGDSVSCPQSII VEYHQDRVVLTRRPVSGVMTNQIIF NNKVVSPGFQQNGIVTSRVGIKMYV TIQEIGVRVMFSGLIFSVEV PFNLFANNTEGQCGTCTNDKKDECR LPGGSIASSCSEMSLHWKVPNQPSC QGPPPTPTSVVPRPSPTPCP PSPLCELILSNTFKLCHDVIPPLQF YQGCLFDYCHMLDLEVVCSGLELYA SLCAAQGVCIPWRSQTNNTC SFTCPDNQVYQPCGPSNPHYCYRDD SISPSLTLQEAGPKTEGCFCPDSTT LFSTNDSICVPSCQWCLGPR GEPVEPGHTISIDCQDCICKEATLT CQKKACPQPTCPEPGFVPVPVALEA GQCCPQFSCACNSSHCPPPL HCPKNSSLIVTYEEGACCPTQNCSS QKGCEVNGTLYQPGDVVSSSLCERC LCEVSSNPLSDVFMVSCETE LCNTQCPKGSEYQAMPGQCCGKCIP KTCPFKNNSGSTYFYQPGELWAEPG NPCVTHKCEKFQDVLMVVTM KTECPKINCPQGQAQLREDGCCYDC PLPNQQKCTVHQRQQIIRQQNCSSE GPVSISYCQGNCGDSISMYS LEANKVEHTCECCQELQTSQRNVTL RCDDGSSQTFSYTQVEKCGCLGQQC HALGDTSHAESSEQEFKSKE SEEHGQQLAFRVSEDMLGPFQ TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Applications: Cell culture: For culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 ug/mL as determined by microplate Bradford method.

Gene Information

• Gene Name: MUC5AC mucin 5AC, oligomeric mucus/gel-forming [ Homo sapiens (human) ]
• Official Symbol: MUC5AC
• Synonyms: TBM; leB; MUC5; mucin
• Gene ID: 4586
• mRNA Refseq: NM_001304359.2
• Protein Refseq: NP_001291288.1
• MIM: 158373
• UniProt ID: P98088