Recombinant Full Length Human NKX2-1 Protein, GST-tagged
Cat.No. : | NKX2-1-6855HF |
Product Overview : | Recombinant full-length human NKX2-1 (1-371) protein with a N-terminal GST-tag was expressed in Wheat Germ(in vitro). |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 65 kDa |
Protein Length : | 371 amino acids |
AA Sequence : | MSMSPKHTTPFSVSDILSPLEESYK KVGMEGGGLGAPLAAYRQGQAAPPT AAMQQHAVGHHGAVTAAYHMTAAGV PQLSHSAVGGYCNGNLGNMSELPPY QDTMRNSASGPGWYGANPDPRFPAI SRFMGPASGMNMSGMGGLGSLGDVS KNMAPLPSAPRRKRRVLFSQAQVYE LERRFKQQKYLSAPEREHLASMIHL TPTQVKIWFQNHRYKMKRQAKDKAA QQQLQQDSGGGGGGGGTGCPQQQQA QQQSPRRVAVPVLVKDGKPCQAGAP APGAASLQGHAQQQAQHQAQAAQAA AAAISVGSGGAGLGAHPGHQPGSAG QSPDLAHHAASPAALQGQVSSLSHL NSSGSDYGTMSCSTLLYGRTW |
Applications : | AP, Array, ELISA, WB-Re |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer |
Gene Name : | NKX2-1 NK2 homeobox 1 [ Homo sapiens (human) ] |
Official Symbol : | NKX2-1 |
Synonyms : | NKX2-1; NK2 homeobox 1; BCH; BHC; NK-2; TEBP; TTF1; NKX2A; NMTC1; T/EBP; TITF1; TTF-1; NKX2.1; homeobox protein Nkx-2.1; NK-2 homolog A; homeobox protein NK-2 homolog A; thyroid nuclear factor 1; thyroid transcription factor 1; thyroid-specific enhancer-binding protein |
Gene ID : | 7080 |
mRNA Refseq : | NM_001079668 |
Protein Refseq : | NP_001073136 |
MIM : | 600635 |
UniProt ID : | P43699 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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