Recombinant Full Length Human NR2E1 Protein, GST-tagged

• Cat.No.: NR2E1-6738HF
• Product Overview: Human NR2E1 full-length ORF ( NP_003260.1, 1 a.a. - 385 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is an orphan receptor involved in retinal development. The encoded protein also regulates adult neural stem cell proliferation and may be involved in control of aggressive behavior. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 69 kDa
• Protein Length: 385 amino acids
• AA Sequence: MSKPAGSTSRILDIPCKVCGDRSSG KHYGVYACDGCSGFFKRSIRRNRTY VCKSGNQGGCPVDKTHRNQCRACRL KKCLEVNMNKDAVQHERGPRTSTIR KQVALYFRGHKEENGAAAHFPSAAL PAPAFFTAVTQLEPHGLELAAVSTT PERQTLVSLAQPTPKYPHEVNGTPM YLYEVATESVCESAARLLFMSIKWA KSVPAFSTLSLQDQLMLLEDAWREL FVLGIAQWAIPVDANTLLAVSGMNG DNTDSQKLNKIISEIQALQEVVARF RQLRLDATEFACLKCIVTFKAVPTH SGSELRSFRNAAAIAALQDEAQLTL NSYIHTRYPTQPCRFGKLLLLLPAL RSISPSTIEEVFFKKTIGNVPITRL LSDMYKSSDI
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: NR2E1 nuclear receptor subfamily 2, group E, member 1 [ Homo sapiens ]
• Official Symbol: NR2E1
• Synonyms: NR2E1; nuclear receptor subfamily 2, group E, member 1; TLX; nuclear receptor subfamily 2 group E member 1; TLL; XTLL; hTll; tailless homolog; nuclear receptor TLX; tailes-related receptor; protein tailless homolog
• Gene ID: 7101
• mRNA Refseq: NM_003269
• Protein Refseq: NP_003260
• MIM: 603849
• UniProt ID: Q9Y466

Reviews

10/11/2022

Its unique properties make NR2E1 an invaluable tool for investigating cellular signaling pathways, protein-protein interactions, and membrane dynamics.

06/23/2018

With the NR2E1 protein and its accompanying technical assistance, I am confident that I can achieve successful outcomes for my research endeavors.

10/28/2017

The NR2E1 protein offers numerous advantages in trials and research studies, making it an excellent choice for scientists in need of reliable and high-quality experimental materials.

Q&As

Can NR2E1 be a target for cancer therapy?

Some studies suggest that NR2E1 may have implications in cancer therapy, particularly in the context of glioblastoma and other brain tumors.

Write 15 questions and answers about the clinical application of GATA1 protein in English

NR2E1 is being investigated for its potential therapeutic applications in neurological disorders, including neurodegenerative diseases and brain injuries.

Can NR2E1 be a potential target for regenerative medicine?

The regulatory role of NR2E1 in neural stem cells makes it a potential target for regenerative medicine strategies aimed at repairing and replacing damaged neural tissue.

How is NR2E1 linked to retinoid signaling pathways?

NR2E1 is known to interact with retinoid signaling pathways, and its activity is influenced by retinoic acid, suggesting a connection to cellular differentiation processes.

How does NR2E1 influence the development of the central nervous system?

NR2E1 regulates the development of the central nervous system by modulating the fate of neural progenitor cells and influencing the formation of various brain structures.