Recombinant Full Length Human NR4A1 Protein, C-Flag-tagged

• Cat.No.: NR4A1-61HFL
• Product Overview: Recombinant Full Length Human NR4A1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 64.3 kDa
• AA Sequence: MPCIQAQYGTPAPSPGPRDHLASDP LTPEFIKPTMDLASPEAAPAAPTAL PSFSTFMDGYTGEFDTFLYQ LPGTVQPCSSASSSASSTSSSSATS PASASFKFEDFQVYGCYPGPLSGPV DEALSSSGSDYYGSPCSAPS PSTPSFQPPQLSPWDGSFGHFSPSQ TYEGLRAWTEQLPKASGPPQPPAFF SFSPPTGPSPSLAQSPLKLF PSQATHQLGEGESYSMPTAFPGLAP TSPHLEGSGILDTPVTSTKARSGAP GGSEGRCAVCGDNASCQHYG VRTCEGCKGFFKRTVQKNAKYICLA NKDCPVDKRRRNRCQFCRFQKCLAV GMVKEVVRTDSLKGRRGRLP SKPKQPPDASPANLLTSLVRAHLDS GPSTAKLDYSKFQELVLPHFGKEDA GDVQQFYDLLSGSLEVIRKW AEKIPGFAELSPADQDLLLESAFLE LFILRLAYRSKPGEGKLIFCSGLVL HRLQCARGFGDWIDSILAFS RSLHSLLVDVPAFACLSALVLITDR HGLQEPRRVEELQNRIASCLKEHVA AVAGEPQPASCLSRLLGKLP
  ELRTLCTQGLQRIFYLKLEDLVPPP PIIDKIFMDTLPFTRTRPLEQKLIS EEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
• Protein Pathways: MAPK signaling pathway

Gene Information

• Gene Name: NR4A1 nuclear receptor subfamily 4 group A member 1 [ Homo sapiens (human) ]
• Official Symbol: NR4A1
• Synonyms: HMR; N10; TR3; NP10; GFRP1; NAK-1; NGFIB; NUR77
• Gene ID: 3164
• mRNA Refseq: NM_002135.5
• Protein Refseq: NP_002126.2
• MIM: 139139
• UniProt ID: P22736