Recombinant Full Length Human NTRK2 Protein, C-Flag-tagged
Cat.No. : | NTRK2-1150HFL |
Product Overview : | Recombinant Full Length Human NTRK2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 90.1 kDa |
AA Sequence : | MSSWIRWHGPAMARLWGFCWLVVGF WRAAFACPTSCKCSASRIWCSDPSP GIVAFPRLEPNSVDPENITE IFIANQKRLEIINEDDVEAYVGLRN LTIVDSGLKFVAHKAFLKNSNLQHI NFTRNKLTSLSRKHFRHLDL SELILVGNPFTCSCDIMWIKTLQEA KSSPDTQDLYCLNESSKNIPLANLQ IPNCGLPSANLAAPNLTVEE GKSITLSCSVAGDPVPNMYWDVGNL VSKHMNETSHTQGSLRITNISSDDS GKQISCVAENLVGEDQDSVN LTVHFAPTITFLESPTSDHHWCIPF TVKGNPKPALQWFYNGAILNESKYI CTKIHVTNHTEYHGCLQLDN PTHMNNGDYTLIAKNEYGKDEKQIS AHFMGWPGIDDGANPNYPDVIYEDY GTAANDIGDTTNRSNEIPST DVTDKTGREHLSVYAVVVIASVVGF CLLVMLFLLKLARHSKFGMKDFSWF GFGKVKSRQGVGPASVISND DDSASPLHHISNGSNTPSSSEGGPD AVIIGMTKIPVIENPQYFGITNSQL KPDTFVQHIKRHNIVLKREL GEGAFGKVFLAECYNLCPEQDKILV AVKTLKDASDNARKDFHREAELLTN LQHEHIVKFYGVCVEGDPLI MVFEYMKHGDLNKFLRAHGPDAVLM AEGNPPTELTQSQMLHIAQQIAAGM VYLASQHFVHRDLATRNCLV GENLLVKIGDFGMSRDVYSTDYYRV GGHTMLPIRWMPPESIMYRKFTTES DVWSLGVVLWEIFTYGKQPW YQLSNNEVIECITQGRVLQRPRTCP QEVYELMLGCWQREPHMRKNIKGIH TLLQNLAKASPVYLDILGTRTRPLE QKLISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome, Protein Kinase, Transmembrane |
Protein Pathways : | MAPK signaling pathway, Neurotrophin signaling pathway |
Gene Name : | NTRK2 neurotrophic receptor tyrosine kinase 2 [ Homo sapiens (human) ] |
Official Symbol : | NTRK2 |
Synonyms : | OBHD; TRKB; DEE58; trk-B; EIEE58; GP145-TrkB |
Gene ID : | 4915 |
mRNA Refseq : | NM_006180.6 |
Protein Refseq : | NP_006171.2 |
MIM : | 600456 |
UniProt ID : | Q16620 |
Products Types
◆ Recombinant Protein | ||
NTRK2-24H | Recombinant Human NTRK2 Protein (32-430aa), C-His tagged | +Inquiry |
NTRK2-2937R | Recombinant Rhesus Macaque NTRK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
NTRK2-379H | Recombinant Human NTRK2 Protein, His-tagged | +Inquiry |
NTRK2-469H | Recombinant Human NTRK2 Protein, His-tagged | +Inquiry |
NTRK2-470H | Recombinant Human NTRK2 Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
NTRK2-1024CCL | Recombinant Canine NTRK2 cell lysate | +Inquiry |
NTRK2-2683HCL | Recombinant Human NTRK2 cell lysate | +Inquiry |
NTRK2-1843MCL | Recombinant Mouse NTRK2 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1629 | TrkB Functional Assay Kit | +Inquiry |
Kit-1547 | U2OS TrkB Bioassay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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