| Description : |
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described. |
| Source : |
In Vitro Cell Free System |
| Species : |
Human |
| Form : |
Liquid |
| Molecular Mass : |
92.180kDa inclusive of tags |
| Protein Length : |
601 amino acids |
| AA Sequence : |
MAGASELGTGPGAAGGDGDDSLYPIAVLIDELRNEDVQLR LNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLA LAEQLGNFTGLVGGPDFAHCLLPPLENLATVEETVVRDKA VESLRQISQEHTPVALEAYFVPLVKRLASGDWFTSRTSAC GLFSVCYPRASNAVKAEIRQQFRSLCSDDTPMVRRAAASK LGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEAC VSIAQLLSQDDLETLVMPTLRQAAEDKSWRVRYMVADRFS ELQKAMGPKITLNDLIPAFQNLLKDCEAEVRAAAAHKVKE LGENLPIEDRETIIMNQILPYIKELVSDTNQHVKSALASV IMGLSTILGKENTIEHLLPLFLAQLKDECPDVRLNIISNL DCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMP LLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMK LVQKFGTEWAQNTIVPKVLVMANDPNYLHRMTTLFCINAL SEACGQEITTKQMLPIVLKMAGDQVANVRFNVAKSLQKIG PILDTNALQGEVKPVLQKLGQDEDMDVKYFAQEAISVLAL A |
| Purity : |
Proprietary Purification |
| Storage : |
Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles. |
| Storage Buffer : |
pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione. |
