Recombinant Full Length Human PTDSS1 Protein, C-Flag-tagged

• Cat.No.: PTDSS1-2014HFL
• Product Overview: Recombinant Full Length Human PTDSS1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene catalyzes the formation of phosphatidylserine from either phosphatidylcholine or phosphatidylethanolamine. Phosphatidylserine localizes to the mitochondria-associated membrane of the endoplasmic reticulum, where it serves a structural role as well as a signaling role. Defects in this gene are a cause of Lenz-Majewski hyperostotic dwarfism. Two transcript variants encoding different isoforms have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 55.3 kDa
• AA Sequence: MASCVGSRTLSKDDVNYKMHFRMIN EQQVEDITIDFFYRPHTITLLSFTI VSLMYFAFTRDDSVPEDNIW RGILSVIFFFLIISVLAFPNGPFTR PHPALWRMVFGLSVLYFLFLVFLLF LNFEQVKSLMYWLDPNLRYA TREADVMEYAVNCHVITWERIISHF DIFAFGHFWGWAMKALLIRSYGLCW TISITWELTELFFMHLLPNF AECWWDQVILDILLCNGGGIWLGMV VCRFLEMRTYHWASFKDIHTTTGKI KRAVLQFTPASWTYVRWFDP KSSFQRVAGVYLFMIIWQLTELNTF FLKHIFVFQASHPLSWGRILFIGGI TAPTVRQYYAYLTDTQCKRV GTQCWVFGVIGFLEAIVCIKFGQDL FSKTQILYVVLWLLCVAFTTFLCLY GMIWYAEHYGHREKTYSECE DGTYSPEISWHHRKGTKGSEDSPPK HAGNNESHSSRRRNRHSKSKVTNGV GKK TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Transmembrane
• Protein Pathways: Glycerophospholipid metabolism, Metabolic pathways

Gene Information

• Gene Name: PTDSS1 phosphatidylserine synthase 1 [ Homo sapiens (human) ]
• Official Symbol: PTDSS1
• Synonyms: LMHD; PSS1; PSSA
• Gene ID: 9791
• mRNA Refseq: NM_014754.3
• Protein Refseq: NP_055569.1
• MIM: 612792
• UniProt ID: P48651