Recombinant Full Length Human PTX3 Protein, C-Flag-tagged

• Cat.No.: PTX3-1457HFL
• Product Overview: Recombinant Full Length Human PTX3 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the pentraxin protein family. The expression of this protein is induced by inflammatory cytokines in response to inflammatory stimuli in several mesenchymal and epithelial cell types, particularly endothelial cells and mononuclear phagocytes. The protein promotes fibrocyte differentiation and is involved in regulating inflammation and complement activation. It also plays a role in angiogenesis and tissue remodeling. The protein serves as a biomarker for several inflammatory conditions.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 41.8 kDa
• AA Sequence: MHLLAILFCALWSAVLAENSDDYDL MYVNLDNEIDNGLHPTEDPTPCDCG QEHSEWDKLFIMLENSQMRE RMLLQATDDVLRGELQRLREELGRL AESLARPCAPGAPAEARLTSALDEL LQATRDAGRRLARMEGAEAQ RPEEAGRALAAVLEELRQTRADLHA VQGWAARSWLPAGCETAILFPMRSK KIFGSVHPVRPMRLESFSAC IWVKATDVLNKTILFSYGTKRNPYE IQLYLSYQSIVFVVGGEENKLVAEA MVSLGRWTHLCGTWNSEEGL TSLWVNGELAATTVEMATGHIVPEG GILQIGQEKNGCCVGGGFDETLAFS GRLTGFNIWDSVLSNEEIRE
  TGGAESCHIRGNIVGWGVTEIQPHG GAQYVSTRTRPLEQKLISEEDLAAN DILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Secreted Protein

Gene Information

• Gene Name: PTX3 pentraxin 3 [ Homo sapiens (human) ]
• Official Symbol: PTX3
• Synonyms: TSG-14; TNFAIP5
• Gene ID: 5806
• mRNA Refseq: NM_002852.4
• Protein Refseq: NP_002843.2
• MIM: 602492
• UniProt ID: P26022

Reviews

06/23/2022

Using this protein, it was found that its purity was high and there were no obvious impurities.

05/20/2022

PTX3 was observed that its expression level was high, which could meet the experimental requirements.

04/11/2021

Its stability is good, there is no obvious change in the storage and transportation process.

Q&As

How does PTX3 protein work in the immune system?

PTX3 regulates the inflammatory response and immune cell activation by binding to receptors on the surface of inflammatory cells.

What are the interactions of PTX3 protein with other molecules?

PTX3 can perform its function by interacting with other proteins, cytokines, and extracellular matrix molecules.

What are the roles of PTX3 protein in the nervous system?

It has a protective and repairing role in the nervous system and can affect the growth of nerve cells and synapse formation.

What roles does PTX3 protein play in the immune system?

This protein plays a regulatory role in the immune system and can influence the inflammatory response and the activity of immune cells.

Is PTX3 protein involved in any signaling pathways?

Yes, PTX3 can be involved in a variety of signaling pathways that affect cell growth, differentiation, and apoptosis.

How does PTX3 protein regulate cell growth and differentiation?

It can affect signal transduction pathways for cell growth and differentiation by binding to its ligands.