Recombinant Human ABHD6 Protein, His-tagged

• Cat.No.: ABHD6-14H
• Product Overview: Recombinant Human ABHD6 Protein (Trp30-Asp337) with N-His tag was expressed in E. coli.

Specification

• Description: Enables acylglycerol lipase activity. Involved in acylglycerol catabolic process. Predicted to be located in late endosome membrane and lysosomal membrane. Predicted to be integral component of membrane. Predicted to be part of AMPA glutamate receptor complex. Predicted to be active in GABA-ergic synapse; glutamatergic synapse; and mitochondrion. Predicted to be integral component of postsynaptic membrane.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 38.7 kDa
  Accurate Molecular Mass: 38 kDa
• Protein length: Trp30-Asp337
• Purity: > 80%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: ABHD6 abhydrolase domain containing 6, acylglycerol lipase [ Homo sapiens (human) ]
• Official Symbol: ABHD6
• Synonyms: ABHD6; abhydrolase domain containing 6, acylglycerol lipase; monoacylglycerol lipase ABHD6; 2-arachidonoylglycerol hydrolase; abhydrolase domain-containing protein 6; lipase protein; EC 3.1.1.23
• Gene ID: 57406
• mRNA Refseq: NM_020676
• Protein Refseq: NP_065727
• MIM: 616966
• UniProt ID: Q9BV23

Reviews

10/13/2020

Your ABHD6 recombinant protein helped me make some progress in epilepsy research.

Q&As

I want to buy ABHD6 protein with catalytic triad mutation, any suggestions?

Our recombinant ABHD6 protein contains the catalytic triad responsible for 2-AG hydrolysis and can be mutated for amino acids to suit your specific demands.

Which protein family does ABHD6 belong to?

ABHD6 is an integral membrane protein that belongs to the serine hydrolase family.

What diseases is ABHD6 associated with?

As a member of the endocannabinoid signaling system, ABHD6 is associated with several devastating diseases including epilepsy.

Where is ABHD6 most expressed?

Highly expressed in the immune system, especially the spleen and small intestine, then the brain (particularly the cerebral cortex, pituitary gland and hippocampus), in addition, ABHD6 expression in selected cell types may vary with development and sex

There is no ABHD6 protein I want in the product catalog, can it be customized?

Of course, we support custom protein production services.

What tag does your ABHD6 recombinant protein use?

To facilitate affinity chromatography, our ABHD6 proteins are available with your choice of GST, His, or Myc/DDK tags. We can also use other tags depending on your research needs.

Which expression systems do you use for your recombinant ABHD6 protein?

We provide a variety of expression systems including E.coli, HEK293, wheat germ, in vitro cell free system and mammalian cells.