Recombinant Human ABT1 cell lysate
Cat.No. : | ABT1-12HCL |
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Description : | Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA. |
Species : | Human |
Size : | 100 ul |
Storage Buffer : | 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
Applications : | Western Blot; |
Gene Name : | ABT1 activator of basal transcription 1 [ Homo sapiens ] |
Official Symbol : | ABT1 |
Synonyms : | hABT1 |
Gene ID : | 29777 |
mRNA Refseq : | NM_013375.3 |
Protein Refseq : | NP_037507.1 |
UniProt ID : | Q9ULW3 |
Chromosome Location : | 6p22.2 |
Function : | DNA binding;RNA binding;nucleotide binding;protein binding;transcription coactivator activity; |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionABT1 protein structure contains a DNA-binding domain, an activation domain, and a dimerization domain with specific functions.
ABT1 is essential for embryonic development, and its knockout results in embryonic lethality in mice. It plays a role in the differentiation of various embryonic cell types.
ABT1 has been shown to play a crucial role in cell differentiation by regulating the expression of genes involved in this process.
ABT1 protein crystal structure is not experimentally determined yet, but computational modeling studies have predicted it based on homology to other transcription factors.
ABT1 has been shown to be involved in the development and function of the nervous system, with studies suggesting that it may play a role in synaptic plasticity and learning and memory.
ABT1 has been shown to regulate the expression of genes involved in the immune response and plays a role in the development and function of immune cells.
ABT1 knockdown or overexpression has been shown to have various effects on cellular processes, including cell proliferation, differentiation, and apoptosis.
The expression of the ABT1 gene is regulated by several factors, including transcription factors and epigenetic modifications such as DNA methylation and histone modifications.
Yes, ABT1 has been implicated in cancer development, with studies showing that its expression is dysregulated in various types of cancer.
There are currently no known mutations in the ABT1 gene that affect protein structure or function. Further studies are needed to investigate potential mutations and their effects.
Customer Reviews (3)
Write a reviewPerforms excellently in ELISA experiments.
Very stable and reliable in Western Blot experiments.
Shows outstanding performance in immunohistochemistry experiments.
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