Recombinant Human ACAA2 Protein (17-397 aa), His-tagged
Cat.No. : | ACAA2-1316H |
Product Overview : | Recombinant Human ACAA2 Protein (17-397 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Metabolism. Protein Description: Partial. |
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Description : | Abolishes BNIP3-mediated apoptosis and mitochondrial damage. |
Source : | Yeast |
Species : | Human |
Tag : | His |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 42.2 kDa |
Protein length : | 17-397 aa |
AA Sequence : | FGAYGGLLKDFTATDLSEFAAKAAL SAGKVSPETVDSVIMGNVLQSSSDA IYLARHVGLRVGIPKETPALTINRL CGSGFQSIVNGCQEICVKEAEVVLC GGTESMSQAPYCVRNVRFGTKLGSD IKLEDSLWVSLTDQHVQLPMAMTAE NLAVKHKISREECDKYALQSQQRWK AANDAGYFNDEMAPIEVKTKKGKQT MQVDEHARPQTTLEQLQKLPPVFKK DGTVTAGNASGVADGAGAVIIASED AVKKHNFTPLARIVGYFVSGCDPSI MGIGPVPAISGALKKAGLSLKDMDL VEVNEAFAPQYLAVERSLDLDISKT NVNGGAIALGHPLGGSGSRITAHLV HELRRRGGKYAVGSACIGGGQGIAV IIQSTA |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. |
Gene Name : | ACAA2 acetyl-CoA acyltransferase 2 [ Homo sapiens ] |
Official Symbol : | ACAA2 |
Synonyms : | ACAA2; DSAEC; beta-ketothiolase; FLJ35992; FLJ95265; |
Gene ID : | 10449 |
mRNA Refseq : | NM_006111 |
Protein Refseq : | NP_006102 |
MIM : | 604770 |
UniProt ID : | P42765 |
Products Types
◆ Recombinant Protein | ||
Acaa2-1484M | Recombinant Mouse Acaa2 Protein, Myc/DDK-tagged | +Inquiry |
ACAA2-25R | Recombinant Rhesus Macaque ACAA2 Protein, His (Fc)-Avi-tagged | +Inquiry |
ACAA2-89R | Recombinant Rat ACAA2 Protein, His (Fc)-Avi-tagged | +Inquiry |
ACAA2-252H | Recombinant Human ACAA2 Protein, His (Fc)-Avi-tagged | +Inquiry |
ACAA2-719H | Recombinant Human ACAA2 | +Inquiry |
◆ Lysates | ||
ACAA2-9118HCL | Recombinant Human ACAA2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionThe molecular weight of ACAA2 protein is approximately 45 kDa.
ACAA2 expression is upregulated in some types of cancer, including prostate and ovarian cancer.
ACAA2 protein is regulated at the transcriptional level by multiple factors, including PPARs and SREBP-1c.
ACAA2 is predominantly expressed in the liver and adipose tissue.
ACAA2 may have clinical significance in the diagnosis and treatment of metabolic disorders and certain types of cancer.
ACAA2 protein's primary function is to participate in fatty acid and ketone body metabolism.
ACAA2 has been implicated in the development of metabolic disorders, including obesity and type 2 diabetes.
Some known inhibitors of ACAA2 include hexachlorophene and fusicoccin-A, while known activators include medium-chain fatty acids and certain drugs.
ACAA2 catalyzes the transfer of acyl groups between CoA and acyl-CoA substrates.
The three-dimensional structure of ACAA2 protein is characterized by an alpha/beta hydrolase fold.
Customer Reviews (3)
Write a reviewHighly effective in detecting and measuring the activity of protein kinases in kinase assays.
Provides consistent and accurate quantification of the target protein in different assay formats.
Shows excellent performance in detecting and measuring the activity of proteases in protease assays.
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