Recombinant Human ACAD9 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ACAD9-3586H
• Product Overview: ACAD9 MS Standard C13 and N15-labeled recombinant protein (NP_054768) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the acyl-CoA dehydrogenase family. Members of this family of proteins localize to the mitochondria and catalyze the rate-limiting step in the beta-oxidation of fatty acyl-CoA. The encoded protein is specifically active toward palmitoyl-CoA and long-chain unsaturated substrates. Mutations in this gene cause acyl-CoA dehydrogenase family member type 9 deficiency. Alternate splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 68.8 kDa
• AA Sequence: MSGCGLFLRTTAAARACRGLVVSTA NRRLLRTSPPVRAFAKELFLGKIKK KEVFPFPEVSQDELNEINQFLGPVE KFFTEEVDSRKIDQEGKIPDETLEK LKSLGLFGLQVPEEYGGLGFSNTMY SRLGEIISMDGSITVTLAAHQAIGL KGIILAGTEEQKAKYLPKLASGEHI AAFCLTEPASGSDAASIRSRATLSE DKKHYILNGSKVWITNGGLANIFTV FAKTEVVDSDGSVKDKITAFIVERD FGGVTNGKPEDKLGIRGSNTCEVHF ENTKIPVENILGEVGDGFKVAMNIL NSGRFSMGSVVAGLLKRLIEMTAEY ACTRKQFNKRLSEFGLIQEKFALMA QKAYVMESMTYLTAGMLDQPGFPDC SIEAAMVKVFSSEAAWQCVSEALQI LGGLGYTRDYPYERILRDTRILLIF EGTNEILRMYIALTGLQHAGRILTT RIHELKQAKVSTVMDTVGRRLRDSL GRTVDLGLTGNHGVVHPSLADSANK FEENTYCFGRTVETLLLRFGKTIME EQLVLKRVANILINLYGMTAVLSRA SRSIRIGLRNHDHEVLLANTFCVEA YLQNLFSLSQLDKYAPENLDEQIKK VSQQILEKRAYICAHPLDRTCTRTR PLEQKLISEEDLAANDILDYKDDDD KV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ACAD9 acyl-CoA dehydrogenase family member 9 [ Homo sapiens (human) ]
• Official Symbol: ACAD9
• Synonyms: ACAD9; acyl-CoA dehydrogenase family, member 9; acyl Coenzyme A dehydrogenase family, member 9; acyl-CoA dehydrogenase family member 9, mitochondrial; MGC14452; NPD002; very-long-chain acyl-CoA dehydrogenase VLCAD; acyl-Coenzyme A dehydrogenase family, member 9; FLJ23533
• Gene ID: 28976
• mRNA Refseq: NM_014049
• Protein Refseq: NP_054768
• MIM: 611103
• UniProt ID: Q9H845

Reviews

12/23/2019

Provides high-quality results in detecting and measuring the activity of oxidoreductases in oxidoreductase assays.

02/15/2018

Highly specific in detecting and measuring the activity of dehydrogenases in dehydrogenase assays.

Q&As

What is the structure of this protein and how does it relate to its function?

The protein structure of acyl-CoA dehydrogenase family member 9 includes a flavin adenine dinucleotide (FAD) binding domain.

What diseases or disorders are associated with mutations in this protein?

Mutations in this protein are associated with various metabolic disorders, including mitochondrial fatty acid oxidation disorders.

What are the physiological roles of acyl-CoA dehydrogenase family member 9?

The physiological roles of acyl-CoA dehydrogenase family member 9 are still being investigated.

What is the primary function of acyl-CoA dehydrogenase family member 9 protein?

The primary function of acyl-CoA dehydrogenase family member 9 protein is currently unknown.

Are there any known inhibitors or activators of this protein?

There are currently no known inhibitors or activators of this protein.

What research is currently being conducted to further understand the function of acyl-CoA dehydrogenase family member 9?

Research is ongoing to further understand the function and role of acyl-CoA dehydrogenase family member 9 in cellular metabolism and disease.

How does the activity of this protein contribute to cellular metabolism?

The activity of this protein contributes to fatty acid metabolism and energy production.

How is the expression of acyl-CoA dehydrogenase family member 9 regulated?

The expression of acyl-CoA dehydrogenase family member 9 is regulated by a variety of factors, including gene expression and protein degradation pathways.

What is the cellular location of this protein within the cell?

The cellular location of this protein within the cell is the mitochondria.

What are the substrates that can be acted upon by acyl-CoA dehydrogenase family member 9?

Acyl-CoA dehydrogenase family member 9 can act on medium to long-chain fatty acids.