Recombinant Human ACPL2 protein, His-tagged

• Cat.No.: ACPL2-3239H
• Product Overview: Recombinant Human ACPL2 protein(NP_689495.1)(Met1-Phe480), fused with His tag, was expressed in HEK293.

Specification

• Source: HEK293
• Species: Human
• Tag: His
• Form: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
• Molecular Mass: The recombinant human ACPL2 consists of 468 amino acids after removal of the signal peptide and has a predicted molecular mass of 54 kDa. It migrates as an approximately 50 kDa band in SDS-PAGE under reducing conditions.
• Protein Length: Met1-Phe480
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: > 95 % as determined by SDS-PAGE
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: ACPL2 acid phosphatase-like 2 [ Homo sapiens ]
• Official Symbol: ACPL2
• Synonyms: ACPL2; acid phosphatase-like 2; acid phosphatase-like protein 2; FLJ23751
• Gene ID: 92370
• mRNA Refseq: NM_001037172
• Protein Refseq: NP_001032249
• UniProt ID: Q8TE99

Reviews

04/05/2021

Just as they described on the site the package

03/20/2021

Good product.

12/10/2020

Workes great, very good product for a nice price.

07/31/2020

Fast delivery. Happy with purchase.

07/12/2018

This product is exactly as advertised with no issues.

Q&As

How does ACPL2 react with (+)-schisandrin B?

Schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of PXYLP1 mRNA]

Could please list three molecular functions of ACPL2?

Lipid binding, oxidoreductase, and RNA binding.

How deos ACPL2 response to the phosphatase activity and acid phosphatase activity?

Responsible for the 2-O-dephosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature glycosaminoglycan (GAG) chains.

What kind of diseases associated with ACPL2 gene?

 Diseases associated with ACPL2 include Ehlers-Danlos Syndrome, Musculocontractural Type, 2 and Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 1, With Or Without Fractures.

What phenotypes occur when affected by ACPL2?

Body height, body fat distribution, and abnormality of refraction, etc.

What biological process (gene ontology) does ACPL2 gene involved?

They are glycosaminoglycan biosynthetic process, positive regulation of heparan sulfate proteoglycan biosynthetic process, dephosphorylation, and chondroitin sulfate proteoglycan biosynthetic process.

What is the bio-physicochemical properties of ACPL2 gene?

pH dependence: Optimum pH is 5.8.

How does ACPL2 influence the 1,2-dimethylhydrazine?

1, 2-Dimethylhydrazine results in decreased expression of PXYLP1 mRNA

How about he mRNA expression of ACPL2 gene?

Tissue specificity: Widely expressed. Strongly expressed in spleen, fetal liver, moderately in placenta, pancreas, kidney, thymus and colon.

Could please some protein tissue co-expression partners for ACPL2 gene?

C4orf19, TNFAIP1, XKR8, KCNJ2, KDF1, BMP5.